Results of the use of the Ex-PRESS miniature glaucoma implant in technically challenging, advanced glaucoma cases: A clinical pilot study

Wamsley, Sonja; Moster, Marlene R.; Rai, Sushma; Alvim, H.; Fontanarosa, Joann

doi:10.1016/j.ajo.2004.06.024

Cited by 94 publications

(69 citation statements)

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“…The limitations of this study are related to the relatively small number (27) of patients included, although this figure is comparable to that reported in the literature [18,22,24]. The tube was visible on slit-lamp biomicroscopy during the post-operative controls and this could have led to some unavoidable bias in the interpretation of the results and complications.…”

Section: Discussionmentioning

confidence: 60%

“…Other studies reported similar success rates but also significant rates of complications including conjunctival erosion, tube obstruction and device dislocation. In the majority of these complications, the device had to be removed [20,21,24,25]. Based on the initial results, new ideas have led to the design of alternative implantation techniques for the device and the development of a new generation of Ex-PRESS drainage devices.…”

Section: Discussionmentioning

confidence: 99%

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Deep sclerectomy with the Ex-PRESS X-200 implant for the surgical treatment of glaucoma

Bissig

Feusier²,

Mermoud³

et al. 2010

Int Ophthalmol

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The efficacy and safety of a newly designed Ex-PRESS X-200 drainage device for the surgical treatment of glaucoma was evaluated. A clinical, prospective, monocentric, non-randomised, unmasked study on patients with medically uncontrolled glaucoma was performed. A superficial scleral flap was created. A posterior deep sclerectomy (DS) was dissected without opening the Schlemm's canal and an Ex-PRESS X-200 device was inserted under the scleral flap into the anterior chamber to drain aqueous humour into the intrascleral space. Biomicroscopy, best-corrected visual acuity (BCVA), applanation intra-ocular pressure (IOP) measurements, and fundus examination were performed before surgery, on the first day, the first week, and 1, 2, 3, 6, 12 and 18 months after surgery. The mean follow-up was 18.6 ± 2.4 months (mean ± SD) for the 26 eyes that were treated with the Ex-PRESS X-200 device. Preoperatively, the mean BCVA was 0.6 ± 0.3, the mean IOP was 22.0 ± 5.1 mmHg, and the mean number of medications per patients was 2.8 ± 0.8. Eighteen months after surgery the mean BCVA was 0.5 ± 0.4, the mean IOP was reduced to 12.0 ± 3.9 mmHg, and the mean number of medications per patient was 0.6 ± 1.2. Eighty-five percent of patients achieved an IOP \ 18 mmHg with or without medication and 69% without medication. Post-operative complications were hyphaema (15%), Seidel (15%), encysted blebs (54%) and bleb fibrosis in 8% of patients. Mitomycin C(MMC) was administered to 15 patients (58%) with needling being performed on 10 (38%) of these patients. Mid-term results of DS with the Ex-PRESS X-200 implant demonstrated its efficacy in controlling IOP with few post-operative complications in difficult eyes with an increased risk of surgery failure.

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Section: Discussionmentioning

confidence: 60%

Section: Discussionmentioning

confidence: 99%

Deep sclerectomy with the Ex-PRESS X-200 implant for the surgical treatment of glaucoma

Bissig

Feusier²,

Mermoud³

et al. 2010

Int Ophthalmol

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show abstract

“…Initially, EXP was implanted at the limbus so that the external portion of the device was only covered by the conjunctiva. This early technique was associated with a high rate of complications, including hypotony, erosion, extrusion and endophthalmitis [38][39][40][41][42]. To avoid these complications, a modified guarded technique was adopted, with the creation of a partial-thickness scleral flap covering the device at the limbus [43].…”

Section: Ahmed Glaucoma Valve Versus Ex-press Shuntsmentioning

confidence: 99%

A Review of the Ahmed Glaucoma Valve Implant and Comparison with Other Surgical Operations

et al. 2017

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The Ahmed glaucoma valve (AGV) is a popular glaucoma drainage implant used for the control of intraocular pressure in patients with glaucoma. While in the past AGV implantation was reserved for glaucoma patients poorly controlled after one or more filtration procedures, mounting evidence has recently encouraged its use as a primary surgery in selected cases. AGV has been demonstrated to be safe and effective in reducing intraocular pressure in patients with primary or secondary refractory glaucoma. Compared to other glaucoma surgeries, AGV implantation has shown favorable efficacy and safety. The aim of this article is to review the results of studies directly comparing AGV with other surgical procedures in patients with glaucoma.

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“…This procedure led to unacceptable hypotony rates in the immediate postoperative stage and medium-term erosion of the device through the conjunctiva. [6][7][8][9][10][11][12] Dahan and Carmichael 13 addressed these issues by placing the device under a partial-thickness scleral flap. The original sub-conjunctival placement has now been completely abandoned for a safer implantation under a scleral flap.…”

Section: Introductionmentioning

confidence: 99%

Comparison of trabeculectomy and Ex-PRESS implantation in fellow eyes of the same patient: a prospective, randomised study

Dahan

Simon

Lafuma

2012

Eye

100

117

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Results of the use of the Ex-PRESS miniature glaucoma implant in technically challenging, advanced glaucoma cases: A clinical pilot study

Cited by 94 publications

References 1 publication

Deep sclerectomy with the Ex-PRESS X-200 implant for the surgical treatment of glaucoma

Deep sclerectomy with the Ex-PRESS X-200 implant for the surgical treatment of glaucoma

A Review of the Ahmed Glaucoma Valve Implant and Comparison with Other Surgical Operations

Comparison of trabeculectomy and Ex-PRESS implantation in fellow eyes of the same patient: a prospective, randomised study

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