Results of surgical treatment of adenocarcinoma of the gastric cardia

Manzoni, Giovanni De; Pedrazzani, Corrado; Pasini, Felice; Leo, Alberto Di; Durante, E; Castaldini, G.; Cordiano, Claudio

doi:10.1016/s0003-4975(01)03571-8

Cited by 58 publications

(44 citation statements)

References 21 publications

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“…The actual TNM classification considers tumors as T3 if they penetrate the visceral peritoneum so even tumors with transmural growth do not always fulfill this condition. Nevertheless, differentiating between tumors with transmural growth and invasion of the perigastric fat and T3 tumors is not essential given their similar clinical behavior and prognosis [20,21]. On this basis a revision of the current staging system has been already proposed [22].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Siewert classification in gastro‐esophageal junction adenocarcinoma: What is the role of endoscopic ultrasonography?

Pedrazzani

Bernini

Giacopuzzi

et al. 2005

Journal of Surgical Oncology

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Section: Discussionmentioning

confidence: 99%

Evaluation of Siewert classification in gastro‐esophageal junction adenocarcinoma: What is the role of endoscopic ultrasonography?

Pedrazzani

Bernini

Giacopuzzi

et al. 2005

Journal of Surgical Oncology

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“…1 However, this practice has been challenged for its prognostic value. [2][3][4] Furthermore, the AJCC 6th staging system was deemed to be flawed with regard to the pN staging system and also inaccurate in predicting patient outcomes after therapy. [5][6][7] To address these challenges, a modified staging scheme was offered in the 7th edition of the AJCC staging system (AJCC 7th), which was published recently.…”

mentioning

confidence: 99%

Gastric cardiac carcinomas involving the esophagus are more adequately staged as gastric cancers by the 7th edition of the American Joint Commission on Cancer Staging System

et al. 2011

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The aim of this study was to compare the 7th with the 6th edition of the American Joint Commission on Cancer Staging System for prognostic stratification of gastric cardiac carcinomas involving the esophagus. We retrospectively compared differences in pathological stages with patient survival between the 7th and the 6th staging systems in 142 consecutive resection cases of this cancer. Patient median age was 65 years. The male-female ratio was 3.3. The epicenter of all tumors was within 5 cm below the gastroesophageal junction. The median tumor size was 5.0 cm. Most tumors (79%) were typical adenocarcinomas and the rest showed uncommon histology types. Using the guidelines for gastric cancer, this group of cancer was better stratified by the 7th than the 6th edition of the staging system, especially for pathological nodal (pN) and overall stage pIIIC. Patients with celiac axis nodal disease had the 5-year survival rate worse than those staged at pN3A and pIIIA. Patients staged at pT3 and pN3B had the 5-year survival rate worse than those at pM1 and pIV. We showed that the overall stage of gastric cardiac carcinomas was better stratified by gastric than by esophageal cancer grouping. We conclude that these tumors are better stratified with the 7th than the 6th edition of the gastric staging system, especially for pIII cancers, and better staged by the new gastric than esophageal cancer staging system. We propose that the staging of these tumors be reverted to gastric grouping and combine pT3 and pN3B into the overall stage pIV.

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“…In our institution the overall morbidity and mortality of operated patients were low, compared with other authors [11][12][13][14]. In the gastric antrum and pylorus tumors the procedure of choice is distal gastrectomy; otherwise in the gastric cardia and corpus tumors the most performed operation is total gastrectomy [2,7,8,[12][13][14].…”

Section: Discussionmentioning

confidence: 73%

“…In Albania, like in other developing countries, gastric cancer is often diagnosed at an advanced stage. Only a curative operation offers hope for cure, but even after a succesful curative resection, the five -year survival rate remain poor [2]. Our present study aims to give a complete overwiew of the surgical treatment of the patients with gastric cancer OPEN …”

Section: Introductionmentioning

confidence: 99%