Results of Revascularization in Patients With Severe Left Ventricular Dysfunction

Mickleborough, Lynda L.; Maruyama, Hiroshi; Takagi, Yasushi; Mohamed, Shanas; Sun, Zhao; Ebisuzaki, Lawrence

doi:10.1161/01.cir.92.9.73

Cited by 137 publications

(103 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…4,7,8,10,15 In our study the hospital mortality was 11%, and only 7% of deaths were cardiac-related, which compares well with most studies. Most of the hospital deaths occurred in the earlier period (early 1990s), and after 2000 only 2 hospital deaths occurred.…”

Section: Discussionsupporting

confidence: 89%

“…Our study indicated that approximately 80% and 45% of patients were alive 5 and 10 years after surgery, respectively. Other studies have reported 5-year survival rates between 60% and 80%, 4,8,9 and 10-year survival rates of approximately 50%. Although the 10-year survival rate is only 40-50%, it is important to note that most of these patients are severely ill with advanced heart failure and it is unlikely that they would have achieved such long-term survival had they been treated with medical treatment alone.…”

Section: Discussionmentioning

confidence: 89%

“…5,6 Many other groups have reported improvements in survival, ventricular function, and functional status after coronary revascularization in patients with severe LV dysfunction. [7][8][9][10] It is believed that the apparent improvements in LVEF, long-term survival, and quality of life following coronary revascularization are related to postoperative myocyte recruitment. Restoration of perfusion resuscitates dormant, viable myocardium and serves to protect the previously functioning portions of the ventricle from further ischemic insults, arrhythmias, and infarction.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Clinical Results of Coronary Revascularization in Left Ventricular Dysfunction

Lee

Chang

Yoo

et al. 2007

Circ J

View full text Add to dashboard Cite

DefinitionsThe number of diseased vessels was defined as the number of the 3 major coronary perfusion territories affected. Perioperative insertion of an intra-aortic balloon pump (IABP) was defined as a procedure for improving hemodynamics in the presence of cardiogenic shock. Postoperative cerebrovascular accident (CVA) was defined as a focal or global neurological deficit confirmed by a neurologist.

show abstract

Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 89%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Clinical Results of Coronary Revascularization in Left Ventricular Dysfunction

Lee

Chang

Yoo

et al. 2007

Circ J

View full text Add to dashboard Cite

show abstract

“…[2][3][4][5][6][7][8][9][10][11][17][18][19] In the present study, the operative mortality rate (7.7%) was almost consistent with those in other studies. Several independent predictors were identifi ed in previous studies for operative death, such as female sex, being elderly, congestive heart failure, advanced NYHA class, nonelective operation, renal failure, and obesity.…”

Section: Discussionsupporting

confidence: 90%

Long-term survival and functional recovery after isolated coronary artery bypass grafting in patients with severe left ventricular dysfunction

Fukui

Shibata

Sasaki

et al. 2007

Gen Thorac Cardiovasc Surg

View full text Add to dashboard Cite

show abstract

“…All scans were reconstructed using FBP with a SheppLogan filter at a voxel dimension of (1 mm) 2 . The same voxel size was used for SIR reconstructions.…”

Section: Iva Numerically Simulated Datasetmentioning

confidence: 99%

Noise spatial nonuniformity and the impact of statistical image reconstruction in CT myocardial perfusion imaging

et al. 2012

View full text Add to dashboard Cite

Purpose: To achieve high temporal resolution in CT myocardial perfusion imaging (MPI), images are often reconstructed using filtered backprojection (FBP) algorithms from data acquired within a short-scan angular range. However, the variation in the central angle from one time frame to the next in gated short scans has been shown to create detrimental partial scan artifacts when performing quantitative MPI measurements. This study has two main purposes.(1) To demonstrate the existence of a distinct detrimental effect in short-scan FBP, i.e., the introduction of a nonuniform spatial image noise distribution; this nonuniformity can lead to unexpectedly high image noise and streaking artifacts, which may affect CT MPI quantification.(2) To demonstrate that statistical image reconstruction (SIR) algorithms can be a potential solution to address the nonuniform spatial noise distribution problem and can also lead to radiation dose reduction in the context of CT MPI. Methods: Projection datasets from a numerically simulated perfusion phantom and an in vivo animal myocardial perfusion CT scan were used in this study. In the numerical phantom, multiple realizations of Poisson noise were added to projection data at each time frame to investigate the spatial distribution of noise. Images from all datasets were reconstructed using both FBP and SIR reconstruction algorithms. To quantify the spatial distribution of noise, the mean and standard deviation were measured in several regions of interest (ROIs) and analyzed across time frames. In the in vivo study, two low-dose scans at tube currents of 25 and 50 mA were reconstructed using FBP and SIR. Quantitative perfusion metrics, namely, the normalized upslope (NUS), myocardial blood volume (MBV), and first moment transit time (FMT), were measured for two ROIs and compared to reference values obtained from a high-dose scan performed at 500 mA. Results: Images reconstructed using FBP showed a highly nonuniform spatial distribution of noise. This spatial nonuniformity led to large fluctuations in the temporal direction. In the numerical phantom study, the level of noise was shown to vary by as much as 87% within a given image, and as much as 110% between different time frames for a ROI far from isocenter. The spatially nonuniform noise pattern was shown to correlate with the source trajectory and the object structure. In contrast, images reconstructed using SIR showed a highly uniform spatial distribution of noise, leading to smaller unexpected noise fluctuations in the temporal direction when a short scan angular range was used. In the numerical phantom study, the noise varied by less than 37% within a given image, and by less than 20% between different time frames. Also, the noise standard deviation in SIR images was on average half of that of FBP images. In the in vivo studies, the deviation observed between quantitative perfusion metrics measured from low-dose scans and high-dose scans was mitigated when SIR was used instead of FBP to reconstruct images. Conclusions: (1) Image...

show abstract

Results of Revascularization in Patients With Severe Left Ventricular Dysfunction

Cited by 137 publications

References 43 publications

Clinical Results of Coronary Revascularization in Left Ventricular Dysfunction

Clinical Results of Coronary Revascularization in Left Ventricular Dysfunction

Long-term survival and functional recovery after isolated coronary artery bypass grafting in patients with severe left ventricular dysfunction

Noise spatial nonuniformity and the impact of statistical image reconstruction in CT myocardial perfusion imaging

Contact Info

Product

Resources

About