Results of renal re-transplant in Spain (1990-2002)

Abstract

Background. Renal re-transplants are increasing in number, due to many first renal transplant patients coming back to dialysis treatment. There are controversial opinions about the evolution of these re-transplanted patients. The aim of our study is to analyse the prognosis of patients and grafts under a renal re-transplant.Methods. This was a retrospective study of 579 renal re-transplants realized in 15 Spanish different centres in the years 1990, 1994, 1998 and 2002 including all renal re-transplants realized in the above-mentioned centres during the same periods.Results. During the follow-up period, 8.81% of patients died. The actuarial patient survival was 85% at 10 years and 80% at 15 years. Principal reasons of death were the same as normal for the renal transplanted patient: cardiovascular (30.77%), infectious (13.46%) and neoplastic (13.46%). During the period of follow-up, 28.6% of the grafts were lost. The actuarial graft survival was 75% at 10 years and 58% at 15 years. Causes of graft loss are very similar to those described in literature.Conclusion. Renal re-transplant is a kind of substitute renal treatment with excellent clinical results that allow to take it as a first-order modality of treatment when the first renal transplant has failed.

Active CMV and EBV infections in renal transplant recipients with unexplained fever and elevated serum creatinine

“…22 It has also been proved that generally active CMV infection occurred in 30-70% of transplant recipients with a mortality rate of 5%. [23][24][25][26][27] Since effective anti-CMV treatment is available and the number of CMV copies well correlated with the severity of clinical symptoms, early detection of CMV DNA in the blood is of great importance in identifying those patients who are at risk of infection and disease progression. 28 Some studies reported co-infection of CMV/EBV.…”