“…Most surgeons preferred cephalexin 500 mg four times a day, and the duration most commonly was 5 to 7 days. Staphylococcus species is the most commonly isolated organism in postoperative infections in patients having general orthopaedic and foot and ankle surgery [3,13,21,39,46,47,52,58,61,65]. This is consistent with the recommendation for a first-generation cephalosporin as preoperative prophylaxis for patients having orthopaedic procedures [2,3,10,52,54], and our participants' preferred cephalexin as their first-line prophylactic postoperative oral antibiotic.…”