Results of Laboratory Screening Tests of Chemical Compounds for Molluscicidal Activity

Nolan, M. O.; Bond, Howard W.

doi:10.4269/ajtmh.1955.4.152

Cited by 8 publications

(3 citation statements)

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“…Immobility, complete retraction into the shell and hypersecretion of mucus prior to death, as observed in snails exposed to lethal concentrations of extracts in the present study, are indicators of molluscicidal poisoning (Nolan et al 1953, Sullivan and Cheng 1975, van Aardt and Coertze 1981, Adewunmi and Ogbe 1986, Evans et al 1986, Duncan 1987, Pretorius et al 1991, Jurberg et al 1995, Bode et al 1996. This is without prejudice to the 'supposed temporary protection' which the mucus appeared to offer by impeding snail contact with the extracts, as it blocked the shell aperture while the viscera were retracted within the shell.…”

Section: Discussionsupporting

confidence: 67%

A laboratory assessment of the potential molluscicidal activity of some Nigerian plant species used as anthelmintics

Adenusi

Odaibo

2010

African Journal of Aquatic Science

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Laboratory studies were conducted to determine the potential molluscicidal activity of five Nigerian plant species used in alternative medicine practice as anthelmintics. Laboratory-bred adult Biomphalaria pfeifferi, the snail host of Schistosoma mansoni in Nigeria, and their viable 0-to 24-hour-old egg masses were separately exposed for 24 hours, in replicated bioassays, to 7.81-4 000 mg l -1 concentrations of crude ethanolic extracts of the leaves and roots of Annona senegalensis, Anogeissus leiocarpus, Crotalaria retusa, Dalbergia sissoo and Vernonia amygdalina. Fruits and stem bark of D. sissoo were also investigated. The 24-hour LC 50 and LC 90 values of extracts for target organisms were calculated using probit analysis. Susceptibility of target organisms to extracts varied with the plant species and morphological part. Egg masses and adult snails were most susceptible to D. sissoo fruit extract (LC 90 values of 89.29 and 74.33 mg l -1 , respectively) and least susceptible to V. amygdalina leaf extract (LC 90 values of 11 864. 09 and 6 241.61 mg l -1 , respectively). Concentration-dependent behavioural responses and embryo deaths at the gastrula/exogastrula and/or prehatch snail stages of development were observed in exposed snails and egg masses, respectively. Tested extracts of A. senegalensis, A. leiocarpus, C. retusa and V. amygdalina did not show appreciable toxicities to B. pfeifferi egg masses or adults. For demonstrating significant molluscicidal activity (LC 90 < 100 mg l -1 ) and toxicities to egg masses, we recommend further studies on the ethanolic extracts of D. sissoo fruits and roots.

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Section: Discussionsupporting

confidence: 67%

A laboratory assessment of the potential molluscicidal activity of some Nigerian plant species used as anthelmintics

Adenusi

Odaibo

2010

African Journal of Aquatic Science

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“…The most abundant resin acid in pine rosin is abietic acid ( 1 , Figure 1), amounting up to 90%. Rosin can be derivatized to an amine mixture (known as Rosin Amine D) containing 60% of (+)-dehydroabietylamine ( 2 , Figure 1) [3,4,5], able to resolve chiral carboxylic acids by crystallization [6,7]. We have previously reported [8] that neutral and ammonium forms of secondary amines derived from dehydroabietylamine may be used in the chiral recognition of enantiomers of certain carboxylic acids.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of Tertiary and Quaternary Amine Derivatives from Wood Resin as Chiral NMR Solvating Agents

2015

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Chiral tertiary and quaternary amine solvating agents for NMR spectroscopy were synthesized from the wood resin derivative (+)-dehydroabietylamine (2). The resolution of enantiomers of model compounds [Mosher's acid (3) and its n-Bu 4 N salt (4)] (guests) by (+)-dehydroabietyl-N,N-dimethylmethanamine (5) and its ten different ammonium salts (hosts) was studied. The best results with 3 were obtained using 5 while with 4 the best enantiomeric resolution was obtained using (+)-dehydroabietyl-N,N-dimethylmethanaminium bis(trifluoromethane-sulfonimide) (6). The compounds 5 and 6 showed a 1:1 complexation behaviour between the host and guest. The capability of 5 and 6 to recognize the enantiomers of various α-substituted carboxylic acids and their n-Bu 4 N salts in enantiomeric excess (ee) determinations was demonstrated. A modification of the RES-TOCSY NMR pulse sequence is described, allowing the enhancement of enantiomeric discrimination when the resolution of multiplets is insufficient.

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“…Os primeiros estudos dos efeitos de compostos químicos sobre o caramujo B. glabrata, no entanto, foram realizados com vista ao estabelecimento de novos moluscicidas para combate da esquistossomose (Fujinami & Nakamura, 1911apud Komiya, 1964 ; Fujinami e Narabayashi, 1913 apud Komiya, 1964 2 ;Narabayashi, 1915 apud Komiya, 1964 3 ;Hoffman & Zakhary, 1953;Nolan et al, 1953;Bond & Nolan, 1954;Nolan & Bond, 1955;Paulini & Camey, 1965a,b).…”

Section: Descrição Ambiental E Comportamental Do B Glabrataunclassified

Estudo da resposta do caramujo Biomphalaria glabrata (Say, 1818) frente a estímulos ambientais estressores, com enfoque na proteína HSP70

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Results of Laboratory Screening Tests of Chemical Compounds for Molluscicidal Activity

Cited by 8 publications

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A laboratory assessment of the potential molluscicidal activity of some Nigerian plant species used as anthelmintics

A laboratory assessment of the potential molluscicidal activity of some Nigerian plant species used as anthelmintics

Synthesis of Tertiary and Quaternary Amine Derivatives from Wood Resin as Chiral NMR Solvating Agents

Estudo da resposta do caramujo Biomphalaria glabrata (Say, 1818) frente a estímulos ambientais estressores, com enfoque na proteína HSP70

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