Results of intradermal tests in horses without atopy and horses with atopic dermatitis or recurrent urticaria

Lorch, Gwendolen; Hillier, Andrew; Kwochka, Kenneth W.; Saville, William A.; LeRoy, Bruce E.

doi:10.2460/ajvr.2001.62.1051

Cited by 48 publications

(57 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Among the animals of atopic dermatitis, the mouse, guinea pig (Fukuda et al, 2003), cat (Schleifer and Willemse, 2003), dog (Mueller et al, 2004) and horse (Lorch et al, 2001) are used. Mouse model of atopic dermatitis gets wider acceptance.…”

Section: Discussionmentioning

confidence: 99%

Mouse model of DNCB-induced atopic dermatitis

Hamad

Han

Rather

2017

Bangladesh J Pharmacol

View full text Add to dashboard Cite

Atopic dermatitis is a skin disease characterized by allergic skin inflammation, redness and itching. The animal model is necessary to find out new drugs. The DNCB-induced animal model of atopic dermatitis includes the following steps: 1) Selection of animals; 2) Shaving of dorsal skin; 3) Applying DNCB once in 24 hours for three days; 4) Monitoring the development of atopy on day 4 post DNCB application. Further, the efficacy of reference drug can be determined by applying on the atopy skin, depends on the nature and aim of the work.

show abstract

Section: Discussionmentioning

confidence: 99%

Mouse model of DNCB-induced atopic dermatitis

Hamad

Han

Rather

2017

Bangladesh J Pharmacol

View full text Add to dashboard Cite

show abstract

“…Blood was drawn for hematology and serum biochemistries. A 40-by 30-cm area was shaved over the right shoulder, and an intradermal test (IDT) was performed using 62 allergens regionalized to Northern California (Table 1) 4 and obtained as concentrates from Greer Laboratories (Lenoir, North Carolina 28645, USA). All allergens were stored in the original glass vials in a standard refrigerator, at approximately 0-4ЊC, and diluted 24 hr before the IDT.…”

Section: Case Reportmentioning

confidence: 99%

“…16 It has been typified best in dogs, 10,16,17 but similar entities have been described in cats 8,12 and horses. 4,5 Steroid-responsive pruritic dermatoses of suspect allergic origin have been reported for llamas (Llama glama). 13 This report describes a case of atopic dermatitis in a Bactrian camel (Camelus bactrianus) where the use of intradermal testing resulted in successful hyposensitization therapy.…”

Section: Introductionmentioning

confidence: 98%

Use of Hyposensitization Injections to Control Seasonal Pruritus in a Bactrian Camel (Camelus Bactrianus)

Gage

Vandenabeele

White³

2005

Journal of Zoo and Wildlife Medicine

View full text Add to dashboard Cite

A 9-yr-old, female Bactrian camel (Camelus bactrianus) developed severe pruritus in June 1993. During the next 8 yr, the camel exhibited annual episodes of pruritus and epiphora, generally beginning in June and subsiding in October of each year. These signs could usually be controlled with topical agents and fly repellents, although pruritus flare-ups were effectively controlled with intermittent injections of diphenhydramine and corticosteroids. There were no signs during the colder months. The pruritus became more severe and difficult to control when the camel reached its 18th year. Histopathologic descriptions of skin biopsies taken from several sites suggested a hypersensitivity reaction with secondary changes because of bacterial infection or corticosteroid administration (or both). An intradermal test (IDT) performed using 62 allergens regionalized to Northern California resulted in 17 positive test sites. Hyposensitization therapy was initiated using allergens chosen on the basis of exposure, availability, and the results of the IDT, using standard protocols. The clinical signs of pruritus were markedly reduced in the 2 yr after the hyposensitization injections were initiated.

show abstract

“…Additionally, exhaled breath condensate has been introduced to evaluate inflammation markers in the lung (Wyse et al, 2005). In the search for potential allergens involved in RAO, an intra-dermal skin test and serum IgE analysis have been evaluated, but these have not proven to be clinically reliable in horses (Lorch et al, 2001;Lebis et al, 2002). Bronchial brushings, BAL, tracheal lavage, exhaled breath condensate, and even lung tissue samples have been shown to be of value in the investigation of the inflammatory process in the equine lung (Bureau et al, 2000;Gerber et al, 2003;Wyse et al, 2005).…”

Section: Investigation Of Horsesmentioning

confidence: 99%