Results of a Living Donor Kidney Promotion Program

Monte, Esther González; Delgado, I. García; Polanco, Natalia; Hernández, Eduardo; Dipalma, T.; Hernández, Ana; Castillo, Maria Carmen Gomez del; Morales, Enrique; Praga, Manuel; Morales, José; Andrés, Amado

doi:10.1016/j.transproceed.2010.09.013

Cited by 9 publications

(3 citation statements)

References 3 publications

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“…Although living organ donation is only used to supplement deceased donation, presenting this option may save the lives of patients who are unlikely to receive an organ from a deceased donor. Indeed, research in Spain has found that the introduction of living organ donation information programs can increase uptake of this type of donation [43]. The use of such programs has the potential to increase living donation, which is likely to help alleviate the shortage of donor organs [44].…”

Section: Discussionmentioning

confidence: 99%

An international comparison of deceased and living organ donation/transplant rates in opt-in and opt-out systems: a panel study

Shepherd

O’Carroll

Ferguson

2014

BMC Med

182

176

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BackgroundPolicy decisions about opt-in and opt-out consent for organ donation are based on limited evidence. To fill this gap we investigated the difference between deceased and living organ donation rates in opt-in and opt-out consent systems across a 13 year period. We controlled for extensive covariates and estimated the causal effect of consent with instrumental variables analysis.MethodThis panel study used secondary data analysis to compare organ donor and transplant rates in 48 countries that had either opt-in or opt-out consent. Organ donation data were obtained over a 13-year period between 2000 and 2012. The main outcome measures were the number of donors, number of transplants per organ and total number (deceased plus living) of kidneys and livers transplanted. The role of consent on donor and transplant rates was assessed using multilevel modeling and the causal effect estimated with instrumental variables analysis.ResultsDeceased donor rates (per-million population) were higher in opt-out (M = 14.24) than opt-in consent countries (M = 9.98; Β = −4.27, 95% confidence interval (CI) = −8.08, −0.45, P = .029). However, the number of living donors was higher in opt-in (M = 9.36) than opt-out countries (M = 5.49; B = 3.86, 95% CI = 1.16, 6.56, P = .006). Importantly, the total number of kidneys transplanted (deceased plus living) was higher in opt-out (M = 28.32) than opt-in countries (M = 22.43; B = −5.89, 95% CI = −11.60, −0.17, P = .044). Similarly, the total number of livers transplanted was higher in opt-out (M = 11.26) than opt-in countries (M = 7.53; B = −3.73, 95% CI = −7.47, 0.01, P = .051). Instrumental variables analysis suggested that the effect of opt-in versus opt-out consent on the difference between deceased and living donor rates is causal.ConclusionsWhile the number of deceased donors is higher than the number of living donors, opt-out consent leads to a relative increase in the total number of livers and kidneys transplanted.

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Section: Discussionmentioning

confidence: 99%

An international comparison of deceased and living organ donation/transplant rates in opt-in and opt-out systems: a panel study

Shepherd

O’Carroll

Ferguson

2014

BMC Med

182

176

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“…3 It would be appropriate to implement programs to increase the attention of health professionals and general population to the field of living donation. 4 Living donation must be integrated into programs of deceased organ donation.…”

Section: Discussionmentioning

confidence: 99%

Living Organ Donation, a Therapeutic Possibility, Is Still Poorly Used in Italy: A National Analysis

Pretagostini

Ricci²,

Gabbrielli

et al. 2012

Transplantation Proceedings

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“…We were unable to perform data extraction in 6 studies. [22][23][24][25][26][27] In one study, the intervention strategy was unclear, 28 and in 5 studies there were no comparator groups. [29][30][31][32][33] Seven abstracts were excluded as full-length publications were not found.…”

Section: Studies Includedmentioning

confidence: 99%

Efficacy of Educational Interventions in Improving Measures of Living-donor Kidney Transplantation Activity: A Systematic Review and Meta-analysis

et al. 2019

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Results of a Living Donor Kidney Promotion Program

Cited by 9 publications

References 3 publications

An international comparison of deceased and living organ donation/transplant rates in opt-in and opt-out systems: a panel study

An international comparison of deceased and living organ donation/transplant rates in opt-in and opt-out systems: a panel study

Living Organ Donation, a Therapeutic Possibility, Is Still Poorly Used in Italy: A National Analysis

Efficacy of Educational Interventions in Improving Measures of Living-donor Kidney Transplantation Activity: A Systematic Review and Meta-analysis

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