Resultados oncológicos, funcionales y complicaciones de la prostatectomía radical transperitoneal asistida por robot

Ihsan-Tasci, A.; Şimşek, Abdülmuttalip; Dogukan-Torer, M.B.; Sökmen, Doğukan; Şahin, Selçuk; Bitkin, Alper; Tuğcu, Volkan

doi:10.1016/j.acuro.2014.02.021

Cited by 4 publications

(8 citation statements)

References 28 publications

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“…These six comparative trials included one RCT 7 , three prospective comparative trials 8 , 9 , 12 , and two retrospective comparative trials 10 , 11 . There were two studies 7 , 9 using laparoscopic RP, two studies 8 , 11 involving robot-assisted RP, and two studies 10 , 12 applying open retropubic RP. The definition of the ITR-NS and ITE-NS in the included studies is presented in Supplementary Table 2 .…”

Section: Resultsmentioning

confidence: 99%

“…The majority of the longitudinal controlled studies were considered to have low to moderate risk of bias (Table 4 ). Three studies 7 , 10 , 11 had the proportion of high Gleason score (8–10 score). Patients in one study 8 who underwent RP were relatively younger than those in other studies included in this meta-analysis.…”

Section: Resultsmentioning

confidence: 99%

“… Study No. of cases, type Method Criterion 3 mo, % 6 mo, % 12 mo, % 36 mo, % Stolzenburg 7 200 ITR-NS ICS 0–1 pads/d 74 87.9 93.2 — 200 ITE-NS 63 76.2 90 — Zheng 9 65 ITR-NS Questionnaire 0–1 pads/d 80.4 87.5 96.6 — 130 ITE-NS 59.8 70.1 94 — Khoder 10 203 ITR-NS Questionnaire 0 pad/d 66 — 90 — 163 ITE-NS 68 — 86 — Ihsan-Tasci 11 200 ITR-NS Not described Only safety pads used — — 80.5 — 41 ITE-NS — — 80.4 — Khoder 12 239 ITR-NS Questionnaire 0 pad/d 56 — 70 85 181 ITE-NS 62 — 61 75 ITR-NS = intrafacial nerve sparing; ITE-NS = interfacial nerve sparing; ICS = International Continence Society.

Figure 2 Forest plot of ( a ) continence rates ( b ) sensitivity analysis for ITR-NS versus ITE-NS.…”

Section: Resultsmentioning

confidence: 99%

“…Three 7 , 10 , 11 studies reported the pT2 PSM rate after the RP (Table 7 ). Low to moderate between-study heterogeneity was detected ( p = 0.27, I 2 = 23%).…”

Section: Resultsmentioning

confidence: 99%

“…One study 7 reported the BCR free rates at 6 mo and four studies 7 , 9 – 11 reported them at 12 mo (Table 8 ). Moderate between-study heterogeneity was detected in the 12 mo point ( p = 0.17, I 2 = 40%).…”

Section: Resultsmentioning

confidence: 99%

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Intrafascial versus interfascial nerve sparing in radical prostatectomy for localized prostate cancer: a systematic review and meta-analysis

Weng

Zeng

Sheng

et al. 2017

Sci Rep

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The present study aimed to systematically evaluate the effectiveness and safety of the intrafascial and interfascial nerve sparing (ITR-NS and ITE-NS) radical prostatectomy. PubMed, Embase, and Cochrane Library databases were searched for eligible studies. Meta-analysis with random-effects model was performed. Six comparative trials were selected and embraced in this research, including one randomized controlled trial, three prospective comparative trials, and two retrospective comparative trials. With regard to perioperative parameters, no significant association of operative time, blood loss, transfusion rates, duration of catheterization, and hospital stay existed between ITR-NS and ITE-NS. With respect to the functional results, ITR-NS had advantages in terms of both continence and potency recovery compared with ITE-NS. In reference to the oncologic results, the ITR-NS showed lower overall positive surgical margin (PSM) compared with ITE-NS but pT2 PSM and biochemical recurrence free rates were similar to the two surgical types. This study demonstrates that ITR-NS has better continence at 6 mo and 36 mo and better potency recovery at 6 mo and 12 mo postoperatively, regardless of the surgical technique. The cancer control of ITR-NS was also better than that of ITE-NS. This may be explained by the fact that patients in ITE-NS group present higher risk cancer than patients in ITR-NS group.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Figure 2 Forest plot of ( a ) continence rates ( b ) sensitivity analysis for ITR-NS versus ITE-NS.…”

Section: Resultsmentioning

confidence: 99%

“…Three 7 , 10 , 11 studies reported the pT2 PSM rate after the RP (Table 7 ). Low to moderate between-study heterogeneity was detected ( p = 0.27, I 2 = 23%).…”

Section: Resultsmentioning

confidence: 99%