Resultados en el tratamiento quirúrgico de los neurinomas del acústico gigantes

Non surgical Treatment of Vestibular Schwannoma

“…14---22 The 5 tumorigeneses after RS of our series occurred during the first 2 years. 7,31,32,34,35 The LC obtained in large tumours of 91% after 5 years, with follow-up of 9.3 years, is similar to that presented by other authors with RS between 87% 6 and 82%. 14,25,26 Local radiological control of the 167 tumours 5 years after treatment is 93%, descending to 90% after 10 years.…”

“…Surgery on these tumours achieved complete resection which ranges between 100% 7 and 87%, 34 with morbidity of the facial nerve between 27% and 72%, LCR fistulas between 5.5% and 14%, a meningitis rate of between 5.5% and 9.5%, and no deaths during surgery. 7,34,37 Although we have controlled the 6 tumours related to NF2, local control in this situation is not normally as good as in sporadic cases, 29,38,39 with a need for additional treatment in 21% of patients treated with RS with a marginal dose of 13.4 Gy.…”

Tratamiento del neurinoma acústico gigante

“…En la serie de Samii y Matthies 7 hubo 11 muertes y 4 en la de Yasargil 18 . Sin embargo, en los últimos años, muchas, si no todas las series quirúrgicas, informan mortalidad «operatoria» cero en acús-ticos grandes y gigantes 8,12,27,29,31,32,40,44 ; en nuestro opinión esto puede deberse una mejora en los criterios de selección de los pacientes de alto riesgo que no son operados (y que por lo tanto no figuran en series quirúrgicas), a una mejora de la técnica quirúrgica y del cuidado postoperatorio o a un sesgo de publicación.…”

Efficiency of Base Excision Repair of Oxidative DNA Damage and Its Impact on the Risk of Colorectal Cancer in the Polish Population

“…Colorectal cancer (CRC) is a common neoplasia in both men and women and is ranked as the second most common type of cancer. The causes of colorectal cancer have not yet been established and its incidence is known to be increasing, with approximately 1.4 million new cases diagnosed each year [ 1 ]. CRC occurs mainly in three specific forms: sporadic form, which accounts for about 80% of all cases, a familial form, which represents about 15%, and inherited forms, observed in 5% of all cases, which include familial adenomatous polyposis (FAP), and hereditary nonpolyposis colorectal cancer (HNPCC) [ 2 ].…”