Restricted Diffusion in Spinal Cord Infarction Demonstrated by Magnetic Resonance Line Scan Diffusion Imaging

Nogueira, Raul G; Ferreira, Rafael; Grant, P. Ellen; Maier, Stephan E.; Koroshetz, Walter J.; González, R Gilberto; Sheth, Kevin N

doi:10.1161/strokeaha.111.624023

Cited by 39 publications

(19 citation statements)

References 12 publications

(15 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…There is no contrast enhancement in the acute stage but there may be patchy enhancement subacutely 7. Restricted diffusion on diffusion-weighted images appears significantly more sensitive than standard T2 imaging8; however, this feature often does not last for more than 1 week and is more difficult to interpret in the spinal cord than the brain due to technical limitations 9. The initial MRI may be negative and so a normal MRI early on does not exclude spinal cord infarction.…”

Section: Hyperacute Onsetmentioning

confidence: 99%

A practical approach to the diagnosis of spinal cord lesions

et al. 2018

View full text Add to dashboard Cite

Every neurologist will be familiar with the patient with atypical spinal cord disease and the challenges of taking the diagnosis forward. This is predominantly because of the limited range of possible clinical and investigation findings making most individual features non-specific. The difficulty in obtaining a tissue diagnosis further contributes and patients are often treated empirically based on local prevalence and potential for reversibility. This article focuses on improving the diagnosis of adult non-traumatic, non-compressive spinal cord disorders. It is structured to start with the clinical presentation in order to be of practical use to the clinician. We aim, by combining the onset phenotype with the subsequent course, along with imaging and laboratory features, to improve the diagnostic process.

show abstract

Section: Hyperacute Onsetmentioning

confidence: 99%

A practical approach to the diagnosis of spinal cord lesions

et al. 2018

View full text Add to dashboard Cite

show abstract

“…In the past decade, new methods such as diffusion imaging of the spinal cord 6,7 allow a better analysis in the acute setting. In this article, we describe the technical protocols, differential diagnosis, pitfalls, and solutions.…”

mentioning

confidence: 99%

Spinal Cord Ischemia: Practical Imaging Tips, Pearls, and Pitfalls

Vargas¹,

Gariani²,

Sztajzel

et al. 2014

AJNR Am J Neuroradiol

157

121

View full text Add to dashboard Cite

SUMMARY:Ischemia of the spinal cord is a rare entity with a poor prognosis. Brain ischemia is no longer a diagnostic challenge; on the contrary, ischemia of the spinal cord remains difficult, particularly in children. In this article, we illustrate the principal causes in children and adults, clinical presentation, different techniques for the diagnosis by MR imaging (diffusion, spinal MR angiography, and 1.5 versus 3T), pathophysiology, and differential diagnosis. We will discuss current knowledge, perspectives, and pitfalls.

show abstract

“…Diffusion-weighted imaging is the most sensitive MRI sequence for cerebral ischaemia, and helps to evaluate patients with suspected spinal cord infarction. However, diffusion-weighted imaging of the spinal cord is technically difficult due to the low signal-to-noise ratio and the effects of motion artefact from cerebrospinal fluid (CSF) flow, breathing and the cardiac cycle 7. As in the brain, areas of acute inflammatory demyelination in the spinal cord can show restricted diffusion, raising issues over the specificity of this imaging method.…”

Section: Commentmentioning

confidence: 99%