Restricted cafeteria feeding and treadmill exercise improved body composition, metabolic profile and exploratory behavior in obese male rats

Alvarez-Monell, Adam; Subias-Gusils, Alex; Mariné-Casadó, Roger; Belda, Xavier; Gagliano, Humberto; Pozo, Óscar J.; Boqué, Noemí; Caimari, Antoni; Armario, Antonio; Solanas, Montserrat; Escorihuela, Rosa M.

doi:10.1038/s41598-022-23464-7

Cited by 3 publications

(7 citation statements)

References 80 publications

(129 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The improvement in biochemical parameters, such as lipoprotein concentrations and profiles were not metformin specific, whereas the glucose tolerance test did not improve in either intervention. Indeed, a recent study showed that rats fed on a calorie-restricted cafeteria diet (30% caloric restriction) did not have decreased circulatory levels of glucose, triglycerides, LDL-cholesterol, and HDL-cholesterol compared to those rats fed on a cafeteria diet without caloric restriction [ 46 ]. Thus, these results suggest that the beneficial effects we observed in mice subjected to the dietary intervention were mediated by the diet change and not by caloric restriction per se.…”

Section: Discussionmentioning

confidence: 99%

Combining Dietary Intervention with Metformin Treatment Enhances Non-Alcoholic Steatohepatitis Remission in Mice Fed a High-Fat High-Sucrose Diet

et al. 2022

View full text Add to dashboard Cite

Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are serious health concerns for which lifestyle interventions are the only effective first-line treatment. Dietary interventions are effective in body weight reduction, but not in improving insulin sensitivity and hepatic lipid mobilization. Conversely, metformin increases insulin sensitivity and promotes the inhibition of de novo hepatic lipogenesis. In this study, we evaluated the metformin effectiveness in NASH prevention and treatment, when combined with dietary intervention in male mice fed a high-fat high-sucrose diet (HFHSD). Eighty 5-week-old C57BL/6J male mice were fed a chow or HFHSD diet and sacrificed at 20 or 40 weeks. The HFHSD-fed mice developed NASH after 20 weeks. Lipoprotein and lipidomic analyses showed that the changes associated with diet were not prevented by metformin administration. HFHSD-fed mice subject to dietary intervention combined with metformin showed a 19.6% body weight reduction compared to 9.8% in those mice subjected to dietary intervention alone. Lower hepatic steatosis scores were induced. We conclude that metformin should not be considered a preventive option for NAFLD, but it is effective in the treatment of this disorder when combined with dietary intervention.

show abstract

Section: Discussionmentioning

confidence: 99%

Combining Dietary Intervention with Metformin Treatment Enhances Non-Alcoholic Steatohepatitis Remission in Mice Fed a High-Fat High-Sucrose Diet

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Training was performed in a treadmill (Columbus instruments, Columbus, OH, USA) as reported in [ 44 ] with some modifications.…”

Section: Methodsmentioning

confidence: 99%

“…Analysis of serum samples was performed as in [ 44 ]. Briefly, enzymatic colorimetric kits were used for the determination of serum total cholesterol, triglycerides, and glucose (QCA, Barcelona, Spain).…”

Section: Methodsmentioning

confidence: 99%

“…Experiment 2 followed a similar design to experiment 1. For detail on the animals used and the experimental design, see [ 44 ]. Of note, the exercise and CAFR interventions started at week 10, the preference test was performed at week 19, the taste reactivity test was performed at week 20, and the brief-access licking test was performed at weeks 21–22.…”

Section: Methodsmentioning

confidence: 99%

“…A similar CAF diet, CAFR diet, and treadmill exercise to experiment 1 were used in experiment 2. For details on the amounts of food and energy administered per day and treadmill training, see [ 44 ]. Of note, the exercise intensity in experiment 2 was set at 12 m/min instead of 17 m/min.…”

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

Impact of Calorie-Restricted Cafeteria Diet and Treadmill Exercise on Sweet Taste in Diet-Induced Obese Female and Male Rats

et al. 2022

Self Cite

View full text Add to dashboard Cite

The goal of the present study was to evaluate the sweet taste function in obese rats fed with a 30% calorie-restricted cafeteria diet (CAFR) and/or subjected to moderate treadmill exercise (12–17 m/min, 35 min, 5 days per week) for 9 weeks. A two-bottle preference test, a taste reactivity test, and a brief-access licking test were carried out when animals were aged 21 weeks; biometric and metabolic parameters were also measured along the interventions. Two separate experiments for females and males were performed. Behaviorally, CAF diet decreased sucrose intake and preference, as well as perceived palatability, in both sexes and decreased hedonic responses in males. Compared to the CAF diet, CAFR exerted a corrective effect on sweet taste variables in females by increasing sucrose intake in the preference test and licking responses, while exercise decreased sucrose intake in both sexes and licking responses in females. As expected, CAF diet increased body weight and Lee index and worsened the metabolic profile in both sexes, whereas CAFR diet ameliorated these effects mainly in females. Exercise had no noticeable effects on these parameters. We conclude that CAF diet might diminish appetitive behavior toward sucrose in both sexes, and that this effect could be partially reverted by CAFR diet in females only, while exercise might exert protective effects against overconsumption of sucrose in both sexes.

show abstract

The Mediating Role of Firm Prestige in the Relationship between Perceived Quality and Behaviour Intention in Customer Cafeteria Experiences

Samsa

2023

MMI

View full text Add to dashboard Cite

Customer experience is viewed from different perspectives as an economic, marketing, management, and competitive strategy. Regardless of the perspective, customer experience is a business strategy and a critical concept that plays a key role in firm success in the 21st century. In recent years, there has been an increasing focus on customer experience as a way for companies to differentiate themselves and build strong relationships with their customers. This approach is based on the idea that companies can build emotional bonds with their customers by providing memorable and positive experiences, leading to greater loyalty, repeat business and positive word-of-mouth. To create these experiences, companies adopt a customer-centric approach that involves understanding their customers’ needs, preferences and behaviours and using this information to design and deliver experiences that exceed their expectations. This approach requires moving away from traditional product-centric or sales-oriented strategies and instead places the customer at the centre of the company’s operations and decision-making processes. From a customer-centric perspective, meeting customer expectations in customer experiences is very important in shaping customer perceptions, attitudes and behaviours. From an experience-based perspective, a study was designed by taking into account the expectancy-affirmation theory, which is a psychological model that explains how customers evaluate their satisfaction with a product or service based on their expectations and perceptions of the experience, and a psychological theory that predicts that meeting customers’ expectations from their experiences may lead to a change in customer behaviour. The study examined the mediating role of firm prestige in the relationship between the perceived quality of customer experiences and customer behaviour intention. For this purpose, data were collected from 230 participants who had cafeteria experience through a questionnaire. The collected data were increased to 5000 by bootstrapping (derivative sampling) through the PLS-SEM algorithm. The study found that store prestige partially mediated the relationship between perceived experience quality and behavioural intention (customer satisfaction/loyalty) but did not mediate the relationship between food quality and behavioural intention (customer satisfaction/loyalty). The study also found that store prestige mediated the relationship between atmosphere quality and service quality, and behavioural intention (customer satisfaction/loyalty). Subsequently, cafeteria management policies should prioritise atmosphere and service quality. These factors directly impact the store’s prestige, leading to customer satisfaction and loyalty.

show abstract

Restricted cafeteria feeding and treadmill exercise improved body composition, metabolic profile and exploratory behavior in obese male rats

Cited by 3 publications

References 80 publications

Combining Dietary Intervention with Metformin Treatment Enhances Non-Alcoholic Steatohepatitis Remission in Mice Fed a High-Fat High-Sucrose Diet

Combining Dietary Intervention with Metformin Treatment Enhances Non-Alcoholic Steatohepatitis Remission in Mice Fed a High-Fat High-Sucrose Diet

Impact of Calorie-Restricted Cafeteria Diet and Treadmill Exercise on Sweet Taste in Diet-Induced Obese Female and Male Rats

The Mediating Role of Firm Prestige in the Relationship between Perceived Quality and Behaviour Intention in Customer Cafeteria Experiences

Contact Info

Product

Resources

About