Restlessness in right upper limb as sole presentation of restless legs syndrome

Gupta, Ravi; Lahan, Vivekananda; Goel, Divya

doi:10.4103/0976-3147.105625

Cited by 8 publications

(17 citation statements)

References 10 publications

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“…Case 124YYYYYYYn.r.n.r. 6 Munhoz et al, 2012; Clin Neurol Neurosurg . Case 224YYYYYn.r.Yn.r.n.r 7 Ruppert et al, 2012; Mov disord25 YYYYYYYNY 8 Gupta et al, 2013; J Neurosci Rural Pract26 YYYYYn.rYNn.r 9 Ruppert et al, 2015; Neurology27 YYYYYYYNY 10 Kim et al, 2017; Acta Neurol Belg28 YYYYYn.rYn.r.n.r. Abbreviations: Y, yes; N, no; n.r., not reported.…”

Section: Resultsunclassified

<p>Restless arms syndrome: prevalence, impact, and management strategies</p>

Ruppert

2019

NDT

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This literature review focuses on restless arms syndrome (RAS), an upper limb variant of restless legs syndrome (RLS). RLS, also known as Willis-Ekbom disease, is a frequently occurring neurological disorder characterized by an irresistible urge to move the lower limbs often accompanied by unpleasant sensations in the legs, worsened at rest and in the evening, improved by movement. Extension of leg restlessness to the upper limbs is frequently reported in typical patients who had RLS only in the legs and usually occurs later in the course of RLS, restlessness remaining most invalidating in the lower limbs. In RAS, the arms are predominantly affected with little or no involvement of the legs. Cases of restless shoulders syndrome or periodic arm movements without arm restlessness were not considered. A total of 9 articles with 10 cases were included and analyzed for the adherence to the five essential diagnostic criteria of the International RLS Study Group (IRLSSG) classification, as well as for the additional supportive features. All of the reported cases were classified as having definite RAS. The clinical history and disease evolution of two previously reported patients were completed and updated. Overall, the clinical picture of RAS does not differ from that of RLS, except for the symptoms localization on the upper limbs. Underlying mechanisms of the spread of RLS to upper limb restlessness and of RAS remain unknown. Whether RAS is a phenotypic variant of RLS or a separate entity needs further investigations. RAS likely remains underdiagnosed and according to IRLSSG diagnostic criteria RAS should be considered when RLS-like symptoms are present in one or both arms, especially when they have a circadian pattern and are improved by movement and dopaminergic therapy. Clinicians should be aware of this rare condition, especially as treatment using dopaminergic agonists proves to be very efficient.

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Section: Resultsunclassified

<p>Restless arms syndrome: prevalence, impact, and management strategies</p>

Ruppert

2019

NDT

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“…The symptoms of depression were not determined to be a cause of the RLS symptoms due to temporal association. Cervical ribs may cause thoracic outlet syndrome (TOS), [6] which…”

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confidence: 99%

“…[1,4,5] In this issue of the Journal of Neuroscience in Rural Practice, the article "Restlessness in right upper limb as sole presentation of restless legs syndrome" demonstrates the primary occurrence of RLS in only one arm. [6] The authors have ruled out other causes of the circadian complaints, and symptoms improved with dopaminergic therapy.…”

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confidence: 99%

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Rémi¹

2013

Journal of Neurosciences in Rural Practice

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“…The clinical case “Restlessness in right upper limb as sole presentation of restless legs syndrome”[1] presented by Gupta and colleaguesin this volumeandissue of the Journal of Neurosciences in Rural Practice refers us to an as-yet debated issue on the pathophysiologyof restless legs syndrome (RLS): Are the neuroanatomical sites of generation of the unpleasant, annoyingsymptoms of the disease peripheral or central?…”

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confidence: 99%

Are symptoms of restless legs syndrome generated in the periphery of the nervous system or are they born centrally?

Pereira

2013

Journal of Neurosciences in Rural Practice

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Restlessness in right upper limb as sole presentation of restless legs syndrome

Cited by 8 publications

References 10 publications

<p>Restless arms syndrome: prevalence, impact, and management strategies</p>

<p>Restless arms syndrome: prevalence, impact, and management strategies</p>

Commentary

Are symptoms of restless legs syndrome generated in the periphery of the nervous system or are they born centrally?

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