Restless sleep disorder in children: a pilot study on a tentative new diagnostic category

DelRosso, Lourdes M.; Bruni, Oliviero; Ferri, Raffaele

doi:10.1093/sleep/zsy102

Cited by 57 publications

(48 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In recent years, the association between iron deficiency and sleep disorders has received growing attention in the scientific literature [ 155 ]. Low levels of iron have been associated with restless legs syndrome/periodic limb movement disorder (RLS/PLMD) [ 156 ] and RLS-induced insomnia [ 157 , 158 ], parasomnias [ 159 ], sleep disordered breathing [ 160 ], attention deficit and hyperactivity disorder (ADHD) [ 161 ], and “restless sleep disorder”, a newly proposed diagnosis [ 162 ].…”

Section: Oral Over-the-counter Medicinesmentioning

confidence: 99%

Sleeping without Prescription: Management of Sleep Disorders in Children with Autism with Non-Pharmacological Interventions and Over-the-Counter Treatments

et al. 2020

Self Cite

View full text Add to dashboard Cite

Autism Spectrum Disorders (ASD) are lifelong neurodevelopmental conditions characterized by abnormal social interaction, communication, and behavior. Sleep disturbances represent a common comorbidity in children and adolescents with ASD, with prevalence ranging from 50 to 80%. It has been proved that sleep disruption worsens the symptoms of autism and results in challenging behaviors. Improving sleep should therefore be a primary therapeutic goal. Treatment options range from lifestyle modifications to pharmacological therapy. Several reviews have been written on pharmacological treatments, but very few on the beneficial effects of non-pharmacological interventions, over-the-counter drugs, and nutritional supplements. This study consists of a narrative review of the literature, presenting the available evidence on the following treatments: sleep education, behavioral interventions, complementary and alternative medicine (special mattresses and blankets, massage, aromatherapy, yoga, physical activity), and commonly used over-the-counter medications and supplements (antihistamines, melatonin, tryptophan, carnosine, iron, vitamins, and herbal remedies). For some treatments—such as melatonin and behavioral interventions—effectiveness in ASD is well established in the literature, while other interventions appear of benefit in clinical practice, even if specific studies in children and adolescents with ASD are lacking. Conversely, other treatments only seem to show anecdotal evidence supporting their use.

show abstract

Section: Oral Over-the-counter Medicinesmentioning

confidence: 99%

Sleeping without Prescription: Management of Sleep Disorders in Children with Autism with Non-Pharmacological Interventions and Over-the-Counter Treatments

et al. 2020

Self Cite

View full text Add to dashboard Cite

show abstract

“…One of our patients had coexistence of RSD with growing pains. Our previous research has shown that children with RSD do not have increased leg motor activation or discomfort (DelRosso et al., ); therefore, we do not have a suspicion of an increased overlap between growing pains and RSD but this might be a topic for future research, if the association proves to be significant.…”

Section: Discussionmentioning

confidence: 81%

“…Although RLS has inherent diagnostic challenges in young children (Picchietti & Stevens, ), video polysomnography has shown a difference in movement patterns in these two groups. Particularly, children with RLS have increased leg movements whereas children with RSD present with large body movements and repositioning (DelRosso et al., ). Although growing pains are not included in the ICSD‐3 sleep diagnosis, we routinely screen for growing pains as the literature has shown an overlap between symptoms of growing pains and RLS (Walters, Gabelia, & Frauscher, ).…”

Section: Discussionmentioning

confidence: 99%

“…We recently identified, in children and adolescents, a potentially new sleep diagnosis called ‘restless sleep disorder’ (RSD), characterized clinically by sleep disruption, frequent nocturnal body movements involving large muscle groups and daytime impairment (DelRosso, Bruni, & Ferri, ). Video‐polysomnographically, patients affected by RSD present with an increased number of body movements (>5/hr), reduced total sleep time and increased number of awakenings, similarly to children with restless legs syndrome (RLS) but without the classic leg movement activity (DelRosso, Jackson, Trotter, Bruni, & Ferri, ).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The prevalence of restless sleep disorder among a clinical sample of children and adolescents referred to a sleep centre

DelRosso

Ferri

2019

Journal of Sleep Research

Self Cite

View full text Add to dashboard Cite

Restless sleep disorder (RSD) is a newly described sleep disorder in children characterized by large body movements and repositioning that lasts all night with at least five body movements per hour and a significant impact on daytime behaviours. The authors have previously identified and described the syndrome and compared the sleep parameters and sleep‐related movements to those in children with restless legs syndrome, normal controls and snorers. The current study is a retrospective review of the sleep diagnosis in 300 consecutive children seen and evaluated in a single sleep disorders centre; 252 children underwent polysomnography, as clinically indicated, to identify the proper diagnosis. The current research estimates the prevalence of RSD in a sleep clinical setting to be 7.7% and compares it to the prevalence of other common sleep disorders in the same setting. Another important addition to the literature is the fact that RSD can coexist with other sleep disorders, such as habitual snoring and parasomnia, without confounding the diagnosis.

show abstract

“…Restless sleep in children has been associated with the development of RLS later in life. 63 Recently, a new entity of restless sleep disorder has been proposed, 64 possibly preceding the development of RLS. Possible RLS: The child is observed to have behavior manifestation of lower extremity discomfort when sitting or lying, accompanied by motor movement of the affected limbs.…”

Section: Epidemiology and Predisposing Factorsmentioning

confidence: 99%

Restless Legs Syndrome and Periodic Limb Movement Disorder in Children

Sharon

Walters

Simakajornboon

2019

JCS

View full text Add to dashboard Cite

Introduction Restless legs syndrome (RLS) and periodic limb movement disorder (PLMD) have been studied more than any other sleep-related movement disorder in the pediatric population. A common feature to both, periodic limb movements, occurs in many other disorders and also in reportedly healthy children and adolescents. In this review, we discuss the different types of limb movements as it pertains to pediatric RLS and PLMD and provides an update on these disorders. Methods A literature search was performed with the following inclusion criteria: English publication, limb movements, leg movements, periodic limb movements of sleep, periodic limb movements during wake, PLMD, RLS, with each of the modifiers, children, pediatric, and adolescents. Identified publications were reviewed and their reference lists were searched for additional relevant publications. Results A total of 102 references were included in this review. These included epidemiological studies, prospective and retrospective studies, case series, observational data, reviews, and consensus guidelines. A critical summary of these findings is presented. Conclusion The limited evidence-based data support the importance of evaluating limb movements in the context of the clinical symptomatology presented by the child or the adolescent. Further research is needed to (1) better understand the pathophysiological mechanisms resulting in periodic limb movements as encountered in the pediatric PLMD or RLS patient and their impact on the overall health and well-being, (2) develop objective diagnostic criteria for RLS and differentiate it from its “mimics” in the pediatric population, and (3) establish evidence-based guidelines for treatment.

show abstract

Restless sleep disorder in children: a pilot study on a tentative new diagnostic category

Cited by 57 publications

References 23 publications

Sleeping without Prescription: Management of Sleep Disorders in Children with Autism with Non-Pharmacological Interventions and Over-the-Counter Treatments

Sleeping without Prescription: Management of Sleep Disorders in Children with Autism with Non-Pharmacological Interventions and Over-the-Counter Treatments

The prevalence of restless sleep disorder among a clinical sample of children and adolescents referred to a sleep centre

Restless Legs Syndrome and Periodic Limb Movement Disorder in Children

Contact Info

Product

Resources

About