Restless legs syndrome is contributing to fatigue and low quality of life levels in hemodialysis patients

Giannaki, Christoforos D.; Hadjigavriel, Michael; Lazarou, Akis; Michael, Aristos; Damianou, Loukas; Atmatzidis, Efthimios; Stefanidis, Ioannis; Hadjigeorgiou, Georgios M.; Sakkas, Giorgos K.; Pantzaris, Marios

doi:10.5527/wjn.v6.i5.236

Cited by 25 publications

(21 citation statements)

References 34 publications

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“…Published studies examining fatigue in CRF patients with RLS are scarce. In a study by Giannak et al, 28 involving 85 dialysis patients, RLS patients reported more severe fatigue, with positive correlations between the RLS severity scale and the fatigue index. When one considers that many HD patients experience intense fatigue symptoms, 29 it becomes clear that effective treatment of RLS, which contributes to fatigue symptoms, may help reduce the severity of fatigue.…”

Section: Discussionmentioning

confidence: 92%

“…When one considers that many HD patients experience intense fatigue symptoms, 29 it becomes clear that effective treatment of RLS, which contributes to fatigue symptoms, may help reduce the severity of fatigue. 28 On the other hand, despite the presence of studies reporting the positive effects of exercise training on fatigue in HD patients, none specifically investigated patients with RLS. 29 Future studies may provide valuable insights on the effects of exercise in uremic patients with RLS.…”

Section: Discussionmentioning

confidence: 99%

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The association between the prevalence of restless leg syndrome, fatigue, and sleep quality in patients undergoing hemodialysis

Türk

Özkurt

Turgal

et al. 2018

SMJ

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Objective:To determine the prevalence of restless legs syndrome (RLS) in patients with chronic renal failure (CRF) and to compare CRF patients with or without RLS in terms fatigue and sleep quality.Methods:A cross-sectional study was conducted on 220 patients (18-75 years) who were undergoing dialysis 3 times weekly in Çorum Province, Corum, Turkey, between January 2014 and January 2016. The diagnosis of RLS was based on the diagnostic form proposed by the international RLS study group. Sleep quality was evaluated using the Pittsburgh sleep quality index (PSQI), and severity of fatigue was determined by using fatigue severity scale (FSS).Results:Of all the participants, 16.8% (n= 37) (Group 1) were found to have RLS, while 183 patients had no RLS (Group 2). The mean ages were similar between groups. With respect to laboratory analyses, a p-value of <0.05 was considered in Group 1 than in Group 2. Restless legs syndrome was mild (7.1%), moderate (46.4%) and severe (39.3%) in patients with RLS. Factors associated with the severity of RLS included weight, duration of dialysis, anuria, iron, total iron binding capacity, calcium and transferrin saturation. The PSQI and FSS scores were significantly worse in Group 1 (p<0.001).Conclusion:Restless legs syndrome is a common condition in patients undergoing hemodialysis; the results of our study confirm the adverse effects of RLS in terms of many aspects of sleep quality and fatigue.

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Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 99%

The association between the prevalence of restless leg syndrome, fatigue, and sleep quality in patients undergoing hemodialysis

Türk

Özkurt

Turgal

et al. 2018

SMJ

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“…These problems affect the different aspects of QOL [12]. In general, physical and social performance disorders decrease the QOL of HD patients [13,14].…”

Section: Introductionmentioning

confidence: 99%

Educational supportive group therapy and the quality of life of hemodialysis patients

Mansouri

Jalali

Rahmati

et al. 2020

BioPsychoSocial Med

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Background In addition to physical, mental, and social condition, ESRD and hemodialysis affect the quality of life of patients as well. Psychotherapy and non-pharmaceutical interventions are effective measures to add meaning to life, create a goal and motivation in life, and improve the quality of life in chronic patients. The effect of educational and supportive group therapy on the quality of life (QOL) of hemodialysis patients was examined. Methods The study was carried out as an interventional quasi-experimental study with the participation of 64 patients who were selected through convenience sampling and based on the patient’s hemodialysis days (Saturday, Monday, and Wednesday patients as an experimental group and Sunday, Tuesday, and Thursday patients as a control group). There were 32 patients in each group. The experimental group received eight 50 min sessions including two sessions per week. The control group received the normal interventions. The participants were assessed using a demographics form and Kidney Disease Quality of Life Short Form before, immediately after, and 1 month after the intervention. The collected data was analyzed using SPSS (v.24). Results The mean QOL scores of the experimental group before, immediately after, and 4 weeks after the intervention were 36.99, 43.3, and 44.9 respectively. Those of the control group were 36.39, 37.2, and 37.1 respectively. There was no significant difference between the two groups before the intervention (P > 0.05); however, the difference between the two groups was significant immediately after and 4 weeks after the intervention (P = 0.0001). The trend of score change in the experimental group was also significant (p < 0.05), and Tukey ad-hoc test showed significant differences between the scores before intervention and those immediately after and 4 weeks after the intervention (p < 0.05). Conclusion In general, educational and supportive group therapy can expand the interpersonal relationships of hemodialysis patients and positively affect their quality of life.

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“…Rohani et al reported that RLS is associated with insomnia, daytime sleepiness, shorter sleep duration, and using sedative-hypnotic medications [25]. Giannaki et al reported that fatigue is a prevalent symptom in chronic renal failure (CRF) patients, but it is more prominent in patients with RLS [26]. Fatigue can be related to impaired sleeping quality and decreased sleeping time in these patients [26].…”

Section: Complications Of Rls and Its Effect On Patient's Lifementioning

confidence: 99%

“…Giannaki et al reported that fatigue is a prevalent symptom in chronic renal failure (CRF) patients, but it is more prominent in patients with RLS [26]. Fatigue can be related to impaired sleeping quality and decreased sleeping time in these patients [26]. Another study by Giannaki et al found that hemodialysis patients with RLS showed atrophy in the thigh muscle compared to patients without RLS [18].…”

Section: Complications Of Rls and Its Effect On Patient's Lifementioning

confidence: 99%

Dialysis Patients With Restless Leg Syndrome: Can We Relieve Their Suffering?

Salib¹,

Memon²,

Gowda³

et al. 2020

Cureus

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Restless leg syndrome (RLS), also called Willis Ekbom disease, can be described as an unpleasant feeling that intensely urges the patients to move their lower limbs. RLS is classified into primary and secondary. It is one of the common complications in hemodialysis patients, and it impairs patients' quality of life. Unfortunately, it is an underdiagnosed and undertreated disorder. In this review article, we performed a literature search using the PubMed database to compare different treatment modalities for RLS in patients with end-stage renal disease (ESRD) on regular hemodialysis. Many of the non-pharmacologic modalities of treatment are cost-effective and safer than pharmacologic therapy. Given the small sample size of the studies and short follow up duration, we should consider conducting studies on a larger number of patients and for longer periods of time to assess the efficacy and safety of different treatment patterns for RLS in hemodialysis patients. We hope to raise awareness about this neurologic condition in hemodialysis patients.

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Restless legs syndrome is contributing to fatigue and low quality of life levels in hemodialysis patients

Cited by 25 publications

References 34 publications

The association between the prevalence of restless leg syndrome, fatigue, and sleep quality in patients undergoing hemodialysis

The association between the prevalence of restless leg syndrome, fatigue, and sleep quality in patients undergoing hemodialysis

Educational supportive group therapy and the quality of life of hemodialysis patients

Dialysis Patients With Restless Leg Syndrome: Can We Relieve Their Suffering?

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