Restless Legs Syndrome: A common disorder, but rarely diagnosed and barely treated - an Indian experience

Gupta, Ravi; Lahan, Vivekananda; Goel, Divya

doi:10.1016/j.sleep.2012.03.018

Cited by 34 publications

(30 citation statements)

References 21 publications

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“…The prevalence of RLS was generally higher for women, almost twice than men in a survey of the general population13,33,44). However, in a survey of population diagnosed with RLS, there was no gender difference in the prevalence of RLS20,36) and we obtained similar results. The occurrence of RLS increases to a peak at age 60 years and then decreases in Western countries and reaches a peak prevalence of 9.1% in the 6th decade of life of Korean adults13).…”

Section: Discussionsupporting

confidence: 78%

Demographic and Clinical Characteristics of Patients with Restless Legs Syndrome in Spine Clinic

Yang

Cho

Kang

et al. 2014

J Korean Neurosurg Soc

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Background: Restless legs syndrome (RLS) is a common condition associated with decreased quality of life in older adults. This study estimates the prevalence, risk factors, and functional correlates of among U.S. elders. Methods: Subjects (n = 1,008) were sub-sampled from the 2002 cross-sectional interview survey of the Health and Retirement Study (HRS), a nationally representative study of U.S. elders. Symptoms and sleep disturbances consistent with RLS were identified. Activities of daily living (ADL), instrumental activities of daily living (IADL), and limitations for mobility, large muscle groups, gross and fine motor function were measured using standardized questions. Incident functional limitations were detected over six years of observation.

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Section: Discussionsupporting

confidence: 78%

Demographic and Clinical Characteristics of Patients with Restless Legs Syndrome in Spine Clinic

Yang

Cho

Kang

et al. 2014

J Korean Neurosurg Soc

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“…Awareness about RLS is poor among medical professionals and diagnosis of RLS was missed not only by general physicians, but also by specialists like neurologists and psychiatrists [22–24]. RLS symptoms are not reported by patients to their health care providers.…”

Section: Discussionmentioning

confidence: 99%

Restless Leg Syndrome in Diabetics Compared with Normal Controls

Zobeiri

Shokoohi

2014

Sleep Disorders

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Introduction. Restless leg syndrome (RLS) is a common sleep disorder which is characterized by urge to move the legs accompanied by disturbing and uncomfortable leg sensation during night and rest. This common condition affects 7–10% of general population and is frequently unrecognized, misdiagnosed, and poorly managed. Several clinical conditions like diabetes have been associated with secondary form of RLS. This study analyzed the frequency and possible risk factor for RLS development in diabetic patient. Material and Methods. This descriptive case-control study was done on 140 consecutive outpatient diabetics and age, sex, and body mass index matched control group. RLS was diagnosed by criteria of the International RLS Study Group. Results. Prevalence of RLS was 28.6% in diabetes and 7.1% in control group (P = 0.001). Sex difference was not significant and with rising duration of diabetes prevalence of RLS was not increased. Discussion. With regarding significant association between RLS and diabetes and its negative impact on quality of life/health outcome/sleep/daytime activity/cognitive function/ and mental state of diabetic patient/higher awareness of RLS among physicians and related health worker suggested.

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“…The symptoms of RLS often degrade normal daily function but are improved with movement (5). RLS is prevalent in 5–10% of the general population (6), although studies have reported rates as high as 11% (9) and 15% (10). …”

Section: Introductionmentioning

confidence: 99%

Nerve Decompression and Restless Legs Syndrome: A Retrospective Analysis

Anderson¹,

Fritz

Benson³

et al. 2017

Front. Neurol.

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IntroductionRestless legs syndrome (RLS) is a prevalent sleep disorder affecting quality of life and is often comorbid with other neurological diseases, including peripheral neuropathy. The mechanisms related to RLS symptoms remain unclear, and treatment options are often aimed at symptom relief rather than etiology. RLS may present in distinct phenotypes often described as “primary” vs. “secondary” RLS. Secondary RLS is often associated with peripheral neuropathy. Nerve decompression surgery of the common and superficial fibular nerves is used to treat peripheral neuropathy. Anecdotally, surgeons sometimes report improved RLS symptoms following nerve decompression for peripheral neuropathy. The purpose of this retrospective analysis was to quantify the change in symptoms commonly associated with RLS using visual analog scales (VAS).MethodsForty-two patients completed VAS scales (0–10) for pain, burning, numbness, tingling, weakness, balance, tightness, aching, pulling, cramping, twitchy/jumpy, uneasy, creepy/crawly, and throbbing, both before and 15 weeks after surgical decompression.ResultsSubjects reported significant improvement among all VAS categories, except for “pulling” (P = 0.14). The change in VAS following surgery was negatively correlated with the pre-surgery VAS for both the summed VAS (r = −0.58, P < 0.001) and the individual VAS scores (all P < 0.01), such that patients who reported the worst symptoms before surgery exhibited relatively greater reductions in symptoms after surgery.ConclusionThis is the first study to suggest improvement in RLS symptoms following surgical decompression of the common and superficial fibular nerves. Further investigation is needed to quantify improvement using RLS-specific metrics and sleep quality assessments.

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Restless Legs Syndrome: A common disorder, but rarely diagnosed and barely treated - an Indian experience

Cited by 34 publications

References 21 publications

Demographic and Clinical Characteristics of Patients with Restless Legs Syndrome in Spine Clinic

Demographic and Clinical Characteristics of Patients with Restless Legs Syndrome in Spine Clinic

Restless Leg Syndrome in Diabetics Compared with Normal Controls

Nerve Decompression and Restless Legs Syndrome: A Retrospective Analysis

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