Restless arms syndrome with oral olanzapine: case based review

Kuang, Qijie; Zhou, Sumiao; Huang, Rumeng; Zheng, Yingjun; She, Shenglin

doi:10.1016/j.heliyon.2022.e12258

Cited by 4 publications

(3 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In 3 cases, psychotropic medication due to a neuropsychiatric diagnosis led to RAS symptoms, and reducing or delaying medication was one of the successful treatment strategies. [8,11,15]. Iron de ciency was found in 2 patients and iron supplementation improved symptoms [10,13].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Title: Dopamine-refractory restless arms syndrome: a case report

Moser,

Westarp

2024

Preprint

View full text Add to dashboard Cite

Background: Restless legs syndrome (RLS) is a common neurological disorder characterised by an uncontrollable urge to move the lower limbs, often accompanied by unpleasant sensations. It typically occurs in the evening and at night and improves with exercise. Restless arm syndrome (RAS) mainly affects the arms and rarely the legs. RAS appears to be very rare, as very few cases have been described. However, RAS may be underdiagnosed, especially when symptoms are mild or transient. A supportive feature for the diagnosis of Restless legs/arms Syndrome (RLS/RAS) is evidence of successful dopaminergic therapy. Case report: This report describes the case of a patient with RAS who failed treatment with L-dopa, dopamine agonists and opioids. Only with the administration of gabapentin was it possible to achieve almost complete freedom from symptoms. Conclusions: Clinicians should be aware of this rare condition, even if treatment with dopaminergic agonists is unsuccessful. A trial of calcium channel 2 ligands may still prove effective.

show abstract

Section: Discussionmentioning

confidence: 99%

“…However, the prevalence of isolated RAS is unknown [3] and only very few cases of arms-only symptoms have been described in the literature [4][5][6][7][8][9][10][11][12][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Title: Dopamine-refractory restless arms syndrome: a case report

Moser,

Westarp

2024

Preprint

View full text Add to dashboard Cite

show abstract

“…Compared to those in RLS patients, sleep disturbances are more prevalent in patients with RLS variants [4]. A close relationship between antipsychotic agents, antidepressants, dopamine therapy and restless arms syndrome (RAS) has been described [5,6]. RAS can be very bothersome and decrease quality of life.…”

Section: Introductionmentioning

confidence: 99%

Suspected Duloxetine-induced restless legs syndrome phenotypic variant: a case report

Shao,

Chen,

Wang

et al. 2024

Preprint

View full text Add to dashboard Cite

Background: Restless arms syndrome (RAS) is the most common variant of restless legs syndrome (RLS), which is easy to be ignored in clinical practice due to the lack of specific diagnostic criteria. When effective therapeutic agents induced RAS and symptoms persisted after briefly observation, clinicians will face the challenge of weighing efficacy against side effects. Case presentation:A 67-year-old woman was admitted to a geriatric psychiatric ward with depression. Upon admission, the escitalopram dose was reduced from 15 mg to 10 mg per day, and the duloxetine dose was increased from 60 mg to 80 mg per day. The next night before bedtime, she developed itching and creeping sensations deep inside bilateral shoulders and arms, with the urge to move, worsening at rest, and alleviation after hammering. The symptoms persisted when escitalopram was discontinued. A history of RLS was confirmed. Treatment with 40 mg of duloxetine and 0.125 mg of pramipexole significantly improved depression, and the paresthesia disappeared, with no recurrence occurring 6 months after discharge. Discussion and conclusions: This case suggests that psychiatrists should pay attention to RLS variants when increasing doses of duloxetine. Long-term improvement can be achieved through dosage reduction combined with dopaminergic drugs instead of immediate discontinuation.

show abstract

Dopamine-refractory restless arms syndrome: a case report

Moser,

Westarp

2024

Discov Med

View full text Add to dashboard Cite

Background Restless legs syndrome (RLS) is a common neurological disorder characterised by an uncontrollable urge to move the lower limbs, often accompanied by unpleasant sensations. It typically occurs in the evening and at night and improves with exercise. Restless arm syndrome (RAS) mainly affects the arms and rarely the legs. RAS appears to be very rare, as very few cases have been described. However, RAS may be underdiagnosed, especially when symptoms are mild or transient. A supportive feature for the diagnosis of Restless legs/arms Syndrome (RLS/RAS) is evidence of successful dopaminergic therapy. Case report This report describes the case of a patient with RAS who failed treatment with L-dopa, dopamine agonists and opioids. Only with the administration of gabapentin was it possible to achieve almost complete freedom from symptoms. Conclusions Clinicians should be aware of this rare condition, even if treatment with dopaminergic agonists is unsuccessful. A trial of calcium channel 2 ligands may still prove effective.

show abstract

Restless arms syndrome with oral olanzapine: case based review

Cited by 4 publications

References 42 publications

Title: Dopamine-refractory restless arms syndrome: a case report

Title: Dopamine-refractory restless arms syndrome: a case report

Suspected Duloxetine-induced restless legs syndrome phenotypic variant: a case report

Dopamine-refractory restless arms syndrome: a case report

Contact Info

Product

Resources

About