Resting-state theta-band connectivity and verbal memory in schizophrenia and in the high-risk state

The Role of Functional Networks in Neuropsychiatric Disorders

“…High-risk individuals displayed intermediate left hemisphere theta connectivity between schizophrenia and healthy controls. The mean theta connectivity within the above network correlated negatively with the verbal memory factor score in all subjects, i.e., increased theta connectivity in left hemisphere regions reflects worse verbal memory performance (Andreou et al 2015). This finding is in line with the hemispheric specification of cortical functions, i.e., word deficits in negative symptoms have close link with functional deficit in the left hemisphere, while face deficits in positive symptoms have close link with functional deficit in the right hemisphere (Burgess and Gruzelier 1997).…”

Cannabinoid–glutamate interactions and neural oscillations: implications for psychosis

“…For example, resting‐state MEG studies have repeatedly found increased delta and theta activity in the temporal lobe, and a positive correlation between temporal lobe theta and positive symptoms (Siekmeier & Stufflebeam, ). In the same line, in a resting‐state EEG study, source analyses revealed that SZ patients displayed increased theta‐band resting‐state connectivity across midline, sensorimotor, orbitofrontal and left temporoparietal junction regions (Andreou et al., ). Furthermore, mean connectivity within this network partially mediated verbal memory deficits.…”

Graph Signal Processing of Low and High-Order Dynamic Functional Connectivity Networks Using EEG Resting-State for Schizophrenia: A Whole Brain Breakdown

“…Interestingly, two studies reported a high correlation between functional connectivity at rest in α frequency band with symptoms in ScZ (Hinkley et al, 2011 ;Merrin and Floyd, 1996). Evidences that contradict have been reported in fast oscillations at β (13-30 Hz) and γ frequencies at rest, including both elevated (Di Lorenzo, et al, 2015), reduced (Kam et al, 2013) and intact (Lehmann et al, 2014, Andreou et al, 2015, Tauscher et al,1998, Winterer et al, 2011 β frequency band connectivity. Preliminary evidence suggests that β based functional connectivity is influenced by illness progression and clinical symptomatology (Di Lorenzo, et al, 2015).…”

“…The majority of studies that explored functional connectivity at α frequency band reported a decreased patter in ScZ. In particular, decreased α connectivity estimated by coherence, lagged coherence and phase synchrony, has been reported at frontal (Di Lorenzo, et al, 2015 ;Tauscher et al,1998), fronto-posterior (Di Lorenzo, et al, 2015, Lehmann et al, 2014 and parieto-temporal (Di Lorenzo, et al, 20150 brain areas (for different results see also Andreou et al, 2015, Kam et al, 2013, Winterer et al, 2011, Merrin and Floyd, 1996. Interestingly, two studies reported a high correlation between functional connectivity at rest in α frequency band with symptoms in ScZ (Hinkley et al, 2011 ;Merrin and Floyd, 1996).…”