Resting-state functional connectivity and pitch identification ability in non-musicians

Hou, Jiancheng; Chen, Chuansheng; Dong, Qi

doi:10.3389/fnins.2015.00007

Cited by 14 publications

(19 citation statements)

References 74 publications

(93 reference statements)

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“…The first 10 volumes of each subject were discarded to allow participants to adapt to the scanning environment. The remaining data were preprocessed including slice timing, head motion correction, and spatial normalization to the standard Montreal Neurological Institute (MNI) space (resampling to 3 × 3 × 3 mm 3 ) [25]. Subsequently, the images were spatially smoothed with a 6 mm full-width at half-maximum (FWHM) Gaussian kernel.…”

Section: Methodsmentioning

confidence: 99%

Relationship between the LHPP Gene Polymorphism and Resting-State Brain Activity in Major Depressive Disorder

et al. 2016

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A single-nucleotide polymorphism at the LHPP gene (rs35936514) has been reported in genome-wide association studies to be associated with major depressive disorder (MDD). However, the neural system effects of rs35936514 that mediate the association are unknown. The present work explores whether the LHPP rs35936514 polymorphism moderates brain regional activity in MDD. A total of 160 subjects were studied: a CC group homozygous for the C allele (23 individuals with MDD and 57 controls) and a T-carrier group carrying the high risk T allele (CT/TT genotypes; 22 MDD and 58 controls). All participants underwent resting-state functional magnetic resonance imaging (rs-fMRI) scanning. Brain activity was assessed using the amplitudes of low-frequency fluctuations (ALFF). MDD patients showed a significant increased ALFF in the left middle temporal gyrus and occipital cortex. The T-carrier group showed increased ALFF in the left superior temporal gyrus. Significant diagnosis × genotype interaction was noted in the bilateral lingual gyri, bilateral dorsal lateral prefrontal cortex (dlPFC), and left medial prefrontal cortex (mPFC) (P < 0.05, corrected). Results demonstrated that MDD patients with LHPP rs35936514 CT/TT genotype may influence the regional brain activity. These findings implicate the effects of the rs35936514 variation on the neural system in MDD.

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Section: Methodsmentioning

confidence: 99%

Relationship between the LHPP Gene Polymorphism and Resting-State Brain Activity in Major Depressive Disorder

et al. 2016

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“…Resting-state analyses have recently provided powerful insights into functional anomalies of various pathologies, including neurodevelopmental disorders such as dyslexia (Schurz et al 2015). Furthermore, first studies investigating brain connectivity at rest in musicians (Fauvel et al 2014;Hou et al 2015;Luo et al 2012) have suggested that experience as a music performer modifies intrinsic brain connectivity, notably by enhancing functional connectivity in the motor and the multisensory cortices, as well as in multiple cognitive networks. For amusia, based on previously reported anatomic abnormalities (Loui et al 2009) and functional coupling changes during auditory protocols (Albouy et al 2013a(Albouy et al , 2015Hyde et al 2011), we predicted underconnectivity of the frontotemporal network at rest.…”

Section: New and Noteworthymentioning

confidence: 99%

Altered intrinsic connectivity of the auditory cortex in congenital amusia

Lévêque

Fauvel

Groussard

et al. 2016

Journal of Neurophysiology

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Congenital amusia, a neurodevelopmental disorder of music perception and production, has been associated with abnormal anatomical and functional connectivity in a right frontotemporal pathway. To investigate whether spontaneous connectivity in brain networks involving the auditory cortex is altered in the amusic brain, we ran a seed-based connectivity analysis, contrasting at-rest functional MRI data of amusic and matched control participants. Our results reveal reduced frontotemporal connectivity in amusia during resting state, as well as an overconnectivity between the auditory cortex and the default mode network (DMN). The findings suggest that the auditory cortex is intrinsically more engaged toward internal processes and less available to external stimuli in amusics compared with controls. Beyond amusia, our findings provide new evidence for the link between cognitive deficits in pathology and abnormalities in the connectivity between sensory areas and the DMN at rest.

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“…Functional connectivity in ACC and MCC has been shown to be more developed in musicians when compared to nonmusicians (Zamorano et al, 2017). Also, Hou and colleagues (Hou, Chen, & Dong, 2015) observed a higher RS‐FC between numerous brain regions, including motor areas and inferior temporal gyrus, middle frontal gyrus, and superior medial frontal cortex in adult nonmusician depending on previous music practice. As previously reported, unlike full‐term newborns, preterm infants are exposed to higher variability of ex‐utero auditory stimulations earlier, including different and unfamiliar adult voices and potentially lullabies or songs.…”

Section: Discussionmentioning

confidence: 96%

Musical memories in newborns: A resting‐state functional connectivity study

Loukas

Lordier

Meskaldji

et al. 2021

Human Brain Mapping

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Music is known to induce emotions and activate associated memories, including musical memories. In adults, it is well known that music activates both working memory and limbic networks. We have recently discovered that as early as during the newborn period, familiar music is processed differently from unfamiliar music. The present study evaluates music listening effects at the brain level in newborns, by exploring the impact of familiar or first‐time music listening on the subsequent resting‐state functional connectivity in the brain. Using a connectome‐based framework, we describe resting‐state functional connectivity (RS‐FC) modulation after music listening in three groups of newborn infants, in preterm infants exposed to music during their neonatal‐intensive‐care‐unit (NICU) stay, in control preterm, and full‐term infants. We observed modulation of the RS‐FC between brain regions known to be implicated in music and emotions processing, immediately following music listening in all newborn infants. In the music exposed group, we found increased RS‐FC between brain regions known to be implicated in familiar and emotionally arousing music and multisensory processing, and therefore implying memory retrieval and associative memory. We demonstrate a positive correlation between the occurrence of the prior music exposure and increased RS‐FC in brain regions implicated in multisensory and emotional processing, indicating strong engagement of musical memories; and a negative correlation with the Default Mode Network, indicating disengagement due to the aforementioned cognitive processing. Our results describe the modulatory effect of music listening on brain RS‐FC that can be linked to brain correlates of musical memory engrams in preterm infants.

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Resting-state functional connectivity and pitch identification ability in non-musicians

Cited by 14 publications

References 74 publications

Relationship between the LHPP Gene Polymorphism and Resting-State Brain Activity in Major Depressive Disorder

Relationship between the LHPP Gene Polymorphism and Resting-State Brain Activity in Major Depressive Disorder

Altered intrinsic connectivity of the auditory cortex in congenital amusia

Musical memories in newborns: A resting‐state functional connectivity study

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