Resting handgrip force and impaired cardiac function at rest and during exercise in COPD patients

Abstract

Handgrip is associated with impaired heart function at rest and during exercise in COPD patients even adjusting for muscle mass differences. Lower handgrip may be a marker of impaired cardiac function in COPD patients.

Handgrip and functional capacity in Chronic Obstructive Pulmonary Disease patients

“…Non-Dominant (% predicted) 106.3 ± 37.5 The HGS also correlated itself significantly and inversely with the BODE Index (Figure 3). It is possible to observe a reduction of HGS related with the worsening of the patients quality of life, which was determined by the quartiles of the BODE index, as described in Table 2, although no significant statistical literature that states that hand grip strength and 6MWT are reduced in patients with COPD particularly in those with hyperinflation (14) and patients with mainly moderate and severe COPD experience a loss of peripheral muscle strength and endurance, exercise capacity and general quality of life (15).…”

Longitudinal Changes in Handgrip Strength, Hyperinflation, and 6-Minute Walk Distance in Patients With COPD and a Control Group

“…Second, other than an electrocardiogram at rest and a negative history of cardiac dysfunction, we did not perform direct evaluation of cardiac function such as an echocardiogram or magnetic resonance, to provide support to some of our statements, but data from other studies with and without lung volume reduction do show a relationship between lung volumes and cardiac function [23][24][25] . First, the number of patients was too small to relate these changes to more important clinical outcomes such as exacerbations, hospitalizations or death.…”

Types of Physical Exercise Training for COPD Patients

“…It is necessary to analyze physical activity in daily life in patients across different disease stages according to GOLD. Other studies have shown that grip strength in the wrist is a strong independent predictor of mortality in COPD (Cortopassi, Divo, Pinto-Plata, & Celli, 2011). A significant relationship was found between hand grip strength and peripheral muscle strength (flexion of elbow and knee) and strong relationship (r = -0.75, p <0.0001) with the force respiratory muscles (maximum inspiratory muscles, inspiratory capacity, forced vital capacity and maximum volume ventilation).…”