Responses of ultra-weak chemiluminescence and secretory IgA in saliva to the induction of angry and depressive moods

Tsuboi, Hirohito; Hamer, Mark; Tanaka, Gohichi; Takagi, Katsuyuki; Kinae, Naohide; Steptoe, Andrew

doi:10.1016/j.bbi.2007.07.006

Cited by 23 publications

(15 citation statements)

References 37 publications

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“…76 In one study of acute stress, individuals who responded with higher ratings of anger and tendency to suppress anger had greater reactive oxygen species 30 minutes after the acute stressor. 77 However, other studies found that acute stress may reduce markers of oxidation. It may be that both the state of a person's health and antioxidant defenses together determine whether acute stress leads to increases or decreases in net oxidation.…”

Section: B3 Insulin Resistance and Adipositymentioning

confidence: 94%

“…71 There are a growing number of studies both in rats 72 and in humans [73][74][75][76] that have found links between markers of oxidative stress and psychological distress. Markers of oxidative stress are increased by acute stress exposure 77,78 as well as by chronic states, such as major depression 79 and duration of exposure to caregiving. 76 In one study of acute stress, individuals who responded with higher ratings of anger and tendency to suppress anger had greater reactive oxygen species 30 minutes after the acute stressor.…”

Section: B3 Insulin Resistance and Adipositymentioning

confidence: 99%

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Psychological and metabolic stress: A recipe for accelerated cellular aging?

Epel

2009

373

329

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Chronic stress can affect human health through a myriad of behavioral and biochemical pathways. Τhis review focuses on some key hormonal and metabolic pathways that appear important today. In modern society, we are faced with excessive psychological stress, as well as an epidemic of overeating, and the two together appear to have synergistic effects. Chronic stress can lead to overeating, co-elevation of cortisol and insulin, and suppression of certain anabolic hormones. This state of metabolic stress in turn promotes abdominal adiposity. Both the direct stress response and the accumulation of visceral fat can promote a milieu of systemic inflammation and oxidative stress. This biochemical environment appears to be conducive to several cell aging mechanisms, mainly dampening telomerase and leading to telomere length (TL) shortening and cell senescence. Immune cell telomere shortness is linked with many chronic disease states and earlier mortality. In this way, chronic stress may influence a variety of diseases through a biochemical cascade leading to immune cell senescence. Certain psychological temperaments at high risk of this stress cascade (mainly anxiety prone), gene-environment interactions, and potential interventions for interrupting the stress-aging cascade are discussed.

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Section: B3 Insulin Resistance and Adipositymentioning

confidence: 94%

Section: B3 Insulin Resistance and Adipositymentioning

confidence: 99%

Psychological and metabolic stress: A recipe for accelerated cellular aging?

Epel

2009

373

329

View full text Add to dashboard Cite

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“…Adult research suggests a modest association between behavioral adjustment and SIgA levels (see review by Valdimarsdottir & Stone, 1997), and an acute depression induction was shown to reduce SIgA levels (Tsuboi et al, 2008). In children, there is scattered evidence that SIgA levels relate to behavioral problems, with children undergoing a stress management intervention showing simultaneous decreases in anxiety and depression and increases in positive mood and SIgA (Hewson-Bower & Drummond, 2001).…”

Section: Secretory Iga Stress Response In Youth: Relations With Otmentioning

confidence: 99%

Secretory IgA reactivity to social threat in youth: Relations with HPA, ANS, and behavior

Laurent

Stroud

Brush

et al. 2015

Psychoneuroendocrinology

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Although the role of immune marker secretory immunoglobulin A (SIgA) in stress-related health outcomes is gaining recognition, SIgA responsiveness to acute stress has rarely been assessed in adults, and not at all in children. This study was designed to clarify developmental origins of differential immune function-related health risks by investigating youth SIgA responses to psychosocial stressors, including both normative responses and variability related to behavioral problems. Children and adolescents from a larger study (n = 82) gave 6 saliva samples during a laboratory session in which they were exposed to a series of performance or interpersonal stressors. Samples were assayed for SIgA, as well as cortisol (representing hypothalamic-pituitary-adrenal axis activity) and alpha-amylase (sAA; representing autonomic nervous system activity). Behavioral problems were assessed with parent-report measures of youth internalizing and externalizing. Youth SIgA trajectories followed a normative pattern of reactivity and recovery around the stressors; however, these responses were blunted in youth with higher externalizing scores. SIgA showed differential associations with cortisol and sAA, and with positive and negative affect; whereas overall levels of SIgA related to cortisol output and positive affect, changes in SIgA over time synchronized with changes in sAA and negative affect. In contrast to SIgA, neither cortisol nor sAA related significantly to behavioral problems. Implications for the role of SIgA during psychosocial stress in the development of immune function-related health risks are discussed.

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“…Salivary IgA is generally considered as an immunity or stress marker, because saliva can be easily collected, noninvasively with little stress. Many studies have demonstrated that salivary IgA concentrations decline with intensive exercise, psychological stress, or aging [2,3,4,5,6,7,8,9,10,11,12,13,14,15]. Moreover, a correlation has been reported between the decline in salivary IgA and the incidence of upper respiratory tract infection (URTI) [16,17,18,19,20,21,22,23,24].…”

mentioning

confidence: 99%

“…However, the spitting method for collecting unstimulated saliva has been the most commonly used collection method in studies examining the relationship between salivary IgA and the incidence of URTI. Salivary IgA is known to exhibit intraindividual and interindividual variations that are influenced by multiple factors, such as saliva collection methods, circadian changes, and lifestyle [2,3,4,5,6,7,8,9,10,11,12,13,14,15, 30]. Thus, more consistent salivary IgA measurements should be obtained for proper evaluation of salivary IgA secretion.…”

mentioning

confidence: 99%

Comparison of Salivary IgA Secretion Rate Collected by the Aspiration Method and Swab Method

Hamuro

Kotani

Toba

et al. 2013

Bioscience of Microbiota, Food and Health

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Salivary immunoglobulin A (IgA) is used as an immunity marker, as saliva can be easily collected, noninvasively with little stress. However, several saliva collection methods can be used. Our comparison between samples collected using different methods demonstrated that the salivary IgA secretion rate in samples collected using an aspiration method was significantly correlated with that in samples collected using a swab method. Moreover, the significant circadian variation in salivary IgA secretion rate in the aspirated saliva suggested that the aspiration method does not suppress salivary IgA secretion rate variability compared with the swab method. Therefore, the aspiration method should be considered as the preferable saliva collection method.

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Responses of ultra-weak chemiluminescence and secretory IgA in saliva to the induction of angry and depressive moods

Cited by 23 publications

References 37 publications

Psychological and metabolic stress: A recipe for accelerated cellular aging?

Psychological and metabolic stress: A recipe for accelerated cellular aging?

Secretory IgA reactivity to social threat in youth: Relations with HPA, ANS, and behavior

Comparison of Salivary IgA Secretion Rate Collected by the Aspiration Method and Swab Method

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