Response to: ‘Statins in systemic lupus erythematosus’ by Abud-Mendoza

Jong, Hilda J. I. de; Staa, Tjeerd van; Tervaert, Jan Willem Cohen

doi:10.1136/annrheumdis-2017-212902

Cited by 1 publication

(1 citation statement)

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“…The importance of studying the consequences of interfering with lipid metabolism in appropriate in vivo models, in particular in combination with standard immunosuppressive medications, is emphasized by the role that lipids play in the immune system, particularly among various cell populations [ 202 ]. Thus, statins, which are lipid-lowering agents, may be used to reduce the risk of atherosclerosis in these patients, but the proven benefit still requires more data to establish the same [ 203 ].…”

Section: Reviewmentioning

confidence: 99%

A Comprehensive Literature Review on Managing Systemic Lupus Erythematosus: Addressing Cardiovascular Disease Risk in Females and Its Autoimmune Disease Associations

Dar,

Koirala,

Khan

et al. 2023

Cureus

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This review aimed to evaluate the mechanism of premature cardiovascular disease (CVD) in systemic lupus erythematosus (SLE) patients, particularly in the female population, and emphasize the need for early management interventions; explore the association between SLE and two autoimmune diseases, myasthenia gravis (MG) and antiphospholipid antibody syndrome (APS), and their management strategies; and evaluate the effectiveness of pharmacological and non-pharmacological interventions in managing SLE, focusing on premenopausal females, females of childbearing age, and pregnant patients. We conducted a comprehensive literature review to achieve these objectives using various databases, including PubMed, Google Scholar, and Cochrane. The collected data were analyzed and synthesized to provide an evidence-based overview of SLE, its management strategies as an independent disease, and some disease associations. The treatment should be focused on remission, preventing organ damage, and improving the overall quality of life (QOL). Extensive emphasis should also be focused on diagnosing SLE and concurrent underlying secondary diseases timely and managing them appropriately.

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Section: Reviewmentioning

confidence: 99%