Response to commentaries

Fekjær, Hans Olav

doi:10.1111/add.12375

Cited by 3 publications

(4 citation statements)

References 10 publications

(7 reference statements)

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“…Although major potential confounders had been adjusted for in previously performed studies, as yet unknown and residual confounding cannot be excluded. Although the evidence for a protective effect of alcohol on the development of RA may be stronger than in other diseases [30], it must be noted that the evidence for the harmful effects of alcohol is far stronger than for any beneficial effect [29]. Consequently, caution must be exercised before promoting a presumed protective effect of alcohol on the development of RA.…”

Section: Discussionmentioning

confidence: 99%

“…Another option for consideration is that there may not, in fact, be a protective effect of alcohol on the risk of the development of RA. Alcohol has been suggested to have protective effects in the development of 29 different chronic diseases [29,30], mainly based on data from observational studies. This view on alcohol as a panacea has recently been challenged, primarily due to the limitations of observational studies such as confounding and classification problems [29,31].…”

Section: Discussionmentioning

confidence: 99%

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Diet and alcohol as risk factors for rheumatoid arthritis: a nested case–control study

2014

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The aim of this study was to investigate whether alcohol and diet, assessed as both macronutrients and dietary patterns, increased the risk of development of rheumatoid arthritis (RA) through a nested case-control design in the Västerbotten Intervention Program (VIP) cohort. Individuals in the VIP who had developed RA after the dietary survey were identified from medical records at the department of rheumatology at the University Hospital, Umeå (n = 386), and matched to 1,886 controls from the same database. Diet was assessed as food groups, as macronutrients and as scores of dietary patterns, namely the carbohydrate-restricted diet score, the Mediterranean diet score and the healthy diet indicator score. When analysing the dietary patterns, consumption of food groups and different macronutrients, a significant association was found in the highest tertile of carbohydrate-restricted diet among the cases with a subsequent anti-CCP-positive disease 1.40 (1.02-1.92), as well as in the highest tertile of protein consumption among smokers (OR = 1.80, 95% CI 1.09-2.95). However, after additional adjustment for sodium intake, these associations were no longer statistically significant. No association was observed between alcohol consumption and the risk of RA. To summarize, there were no significant associations between diet, or alcohol consumption, and the risk of development of RA within this cohort. The lack of any significant associations of alcohol consumption may be explained by a low consumption in the studied population overall or alternatively by methodological issues raised recently.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Diet and alcohol as risk factors for rheumatoid arthritis: a nested case–control study

2014

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“…Furthermore, a Swedish case-control study on 386 patients with pre-clinical RA did not report associations between RA and low alcohol consumption [112]. Despite the observation of a protective effect of moderate alcohol intake on the development of different chronic diseases, including RA, a definitive indication cannot be made, considering several limitations of the available studies, among which confounding factors and classification issues; accordingly, the results of these studies must be interpreted with caution [129][130][131]. A different consideration must be taken for red wine, which has a large content in polyphenols that can reduce inflammation, improve lipid metabolism, antioxidant state, and endothelial function independently from the alcohol content [132].…”

Section: Alcohol and Red Winementioning

confidence: 99%

Dietary Habits and Nutrition in Rheumatoid Arthritis: Can Diet Influence Disease Development and Clinical Manifestations?

et al. 2020

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Rheumatoid arthritis (RA) is a systemic, autoimmune disease characterized by joint involvement, with progressive cartilage and bone destruction. Genetic and environmental factors determine RA susceptibility. In recent years, an increasing number of studies suggested that diet has a central role in disease risk and progression. Several nutrients, such as polyunsaturated fatty acids, present anti-inflammatory and antioxidant properties, featuring a protective role for RA development, while others such as red meat and salt have a harmful effect. Gut microbiota alteration and body composition modifications are indirect mechanisms of how diet influences RA onset and progression. Possible protective effects of some dietary patterns and supplements, such as the Mediterranean Diet (MD), vitamin D and probiotics, could be a possible future adjunctive therapy to standard RA treatment. Therefore, a healthy lifestyle and nutrition have to be encouraged in patients with RA.

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“…En viktig faglig-etisk utfordring som terapeutene rapporterte om, var situasjoner hvor det har forekommet vold i naere relasjoner. Alkohol og/eller annen ruspåvirkning er ofte tilstede når voldsutøvelse skjer (Fekjaer, 2016;Lund, 2014;Norström, 1993). Pape (2011) mener forskningen tyder på at det er hensiktsmessig å samordne behandling for volds-og aggresjonsproblematikk og problemfylt drikking.…”

Section: Faglig-etiske Utfordringerunclassified

«Jeg får et helt annet innblikk»: Fagpersoners erfaringer med familieorientert praksis i rusbehandling

Kalsås

Selbekk

Ness³

2020

Nordic Studies on Alcohol and Drugs

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Aim: Family members' lives and health are seriously affected by alcohol-and drug addiction in close relationships, and research on addiction treatment shows that outcome of treatment is better when family is involved, both for the patient and family member. In Norway, there are clear political and professional guidelines in favour of involvement of family/significant others in the course of treatment, however, there are few addiction treatment services in Norway who comprehensively do so. The aim of this study is to explore therapists' experiences from involving family and significant others in interdisciplinary specialised addiction treatment (TSB), within an inpatient clinic in Norway. The research question is: What significance do therapists emphasise from

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Response to commentaries

Cited by 3 publications

References 10 publications

Diet and alcohol as risk factors for rheumatoid arthritis: a nested case–control study

Diet and alcohol as risk factors for rheumatoid arthritis: a nested case–control study

Dietary Habits and Nutrition in Rheumatoid Arthritis: Can Diet Influence Disease Development and Clinical Manifestations?

«Jeg får et helt annet innblikk»: Fagpersoners erfaringer med familieorientert praksis i rusbehandling

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