Response to “Comment’s on the Story of the Silent Killer, a History of Hypertension: Its Discovery, Diagnosis, Treatment, and Debate”

Kalehoff, Jonathan P; Oparil, Suzanne

doi:10.1007/s11906-020-01123-4

Cited by 15 publications

(27 citation statements)

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“…Globally, HTN continues to be a major risk factor for cardiovascular disease and mortality ( Reboldi et al, 2022 ). HTN is often called the silent killer because it is asymptomatic in many cases and symptoms are difficult to detect without special apparatus, causing around 9.4 million deaths worldwide ( Kalehoff & Oparil, 2020 ; Sayyad et al, 2021 ).…”

Section: Review Of Literaturementioning

confidence: 99%

Knowledge, Attitudes, and Practices of Hypertensive Patients Towards Stroke Prevention Among Rural Population in Saudi Arabia: A Cross-Sectional Study

et al. 2023

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Introduction Stroke is a significant health problem and is considered one of the leading causes of mortality and permanent disability worldwide. Hypertension is a primary risk factor for stroke. Thus, hypertensive patients’ knowledge, attitudes, and practices (KAP) are essential in preventing stroke. Objective To examine hypertensive patients’ KAP towards stroke prevention among rural population in Saudi Arabia. Methods The study utilized a cross-sectional design. The data were collected using a convenience sampling technique from hypertensive patients in the northwestern rural areas of Riyadh Province. A self-administered questionnaire was adapted from the Stroke Recognition Questionnaire (SRQ) and utilized to assess KAP towards stroke prevention among rural hypertensive patients. The STrengthening of the Reporting of OBservational studies in Epidemiology (STROBE) checklist was used to report the study. Results A total of 196 hypertensive patients participated in the study. The total mean scores categorization into three quartiles showed that most respondents had poor levels of KAP towards stroke prevention. Weak positive correlations were found between KAP of patients. There were statistically significant differences between respondents’ attitudes and practices with their age, education, marital status, and occupational status. Discussion This study denoted poor levels of KAP towards stroke prevention among hypertensive patients living in rural areas. This study showed the importance of further considering rural population by which improving their health and quality of life. Extending health educational programs and behavior-changing strategies to rural areas is essential to increase hypertensive patients and general public awareness about their stroke prevention and other health-related concerns.

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Section: Review Of Literaturementioning

confidence: 99%

Knowledge, Attitudes, and Practices of Hypertensive Patients Towards Stroke Prevention Among Rural Population in Saudi Arabia: A Cross-Sectional Study

et al. 2023

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“…21 Participants reported that hypertension had the least impact, which may be due the silent nature of the disease process and/or lack of knowledge of hypertension as a risk factor of heart disease, stroke, and PAD. 22 The hypothesis that greater perceived health condition impact would be associated with impaired mobility was partially confirmed (Table 3). Persons with a SIGAM grade C, who are limited to indoor ambulation of #50 m on even level ground, experienced higher levels of health condition severity than persons who were outdoor higher level ambulators (grades D and F).…”

Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%

Self-reported health condition severity and ambulation status postmajor dysvascular limb loss

Mayo

Viana

Dilkas

et al. 2022

Prosthetics &Amp; Orthotics International

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Background:Individuals with dysvascular lower limb amputations (LLA) secondary to complications of peripheral arterial disease (PAD) and/or diabetes have high rates of co-morbidities.Objectives:To describe self-reported health condition severity and their association with sociodemographic factors and ambulations status among individuals with major dysvascular LLA.Study Design:Cross sectional telephone and in person survey with adults with major dysvascular LLA living in the community setting in Ontario, Canada.Methods:Survey by phone/in person, and completion of the Dysvascular Conditions Scale and Special Interest in Amputee Medicine Mobility (SIGAM) Grade by each participant.Results:Two hundred thirty-one individuals with major dysvascular LLAs participated in the study. Most of them were male individuals (80.5%) and had undergone a transtibial amputation (74%). On average, participants were 3.4 years postlimb loss and had five identified Dysvascular Conditions Scale health conditions. The top five reported health conditions were diabetes, hypertension, phantom limb pain, musculoskeletal pain, and back pain. With the exclusion of hypertension, these conditions were also perceived by respondents to be quite severe for their impact. Vision impairment was also rated as being severe in nature. Lower mobility Special Interest Group in Amputee Medicine grades were associated with higher health condition severity scores.Conclusions:Individuals with dysvascular limb loss experience high multimorbidity with perceived negative impact on their overall wellness and function. Rehabilitation and self-management strategies to help patients with dysvascular LLAs to manage chronic health conditions may improve outcomes.

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“…What constitutes an overt or obvious symptom may be debatable for any particular condition and/or patient and may be influenced by a wide variety of factors. For example, silent diseases may be relatively mild in severity during portions of their existence, allowing them to be insidious in their inception and/or during part of their course, such as is often the case with hypertension, 12 diabetes mellitus, 13 ischemic heart disease, 14 and fatty liver disease. 15 They may affect anatomical regions (including a variety of malignancies, such as breast, 16 kidney, 17 pancreatic, 18 and prostate 19 cancer), and/or physiological functions (eg, impaired renal function in chronic kidney disease 20 ) that are less likely to impart problems that are easily observed by patients or their caregivers, particularly during early or indolent periods of the disease.…”

Section: Defining Silent Ibdmentioning

confidence: 99%

Silent Inflammatory Bowel Disease

Coates

Binion

2021

Crohn's &Amp; Colitis 360

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Inflammatory bowel disease (IBD) is frequently associated with a variety of problematic symptoms, including abdominal pain and bowel habit changes, which are associated with poor patient quality of life and significant healthcare expenditure. Interestingly, silent IBD, a condition where patients demonstrate reduced perception and/or reporting of symptoms in the setting of active inflammation, may be as clinically consequential. This condition has been associated with serious complications leading to more costly interventions. It is by its nature an under-recognized phenomenon that affects substantial portions of patients with either Crohn’s disease or ulcerative colitis. At the present time, although there are a variety of theories relating to the underlying causes and contributors, little is known about why this phenomenon occurs. As a result, there is a lack of cost-effective, reliable diagnostic methods to identify and manage “at-risk” patients. However, it is significantly likely that further study and an improved understanding of this condition will lead to improved approaches for the diagnosis and treatment of patients with silent IBD as well as other gastrointestinal disorders associated with alterations in symptomatic perception. In this article, we critically review studies that have investigated silent IBD. Specifically, we discuss the following: (1) the methods for defining silent IBD, (2) the known epidemiology of silent IBD, (3) potential causes of and contributors to this clinical entity, (4) current diagnostic modalities available to identify it, and (5) gaps in our understanding as well as potential novel diagnostic and therapeutic applications that could be developed with further study of this condition.

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Response to “Comment’s on the Story of the Silent Killer, a History of Hypertension: Its Discovery, Diagnosis, Treatment, and Debate”

Cited by 15 publications

References 0 publications

Knowledge, Attitudes, and Practices of Hypertensive Patients Towards Stroke Prevention Among Rural Population in Saudi Arabia: A Cross-Sectional Study

Knowledge, Attitudes, and Practices of Hypertensive Patients Towards Stroke Prevention Among Rural Population in Saudi Arabia: A Cross-Sectional Study

Self-reported health condition severity and ambulation status postmajor dysvascular limb loss

Silent Inflammatory Bowel Disease

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