Response to antifibrotic therapy and decrease of circulating BAG3 protein levels in systemic sclerosis patients with reduced forced vital capacity

Presence of BAG3 protein in serum samples from patients affected by psoriasis

“…By interacting with different partners, it regulates various cellular functions, including apoptosis, autophagy and motility. Its release is documented in very few pathological conditions: pancreatic cancer [ 2 ]; advanced-stage or acutely decompensated heart failure [ 3 ]; systemic sclerosis [ 4 ]. In our opinion, two features of BAG3 are interesting in relation to the study of psoriasis.…”