Response: Re: Effect of Antibiotics on Vulvovaginal Candidiasis: A Metronet Study

Xu, Jinping

doi:10.3122/jabfm.2009.02.080258

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Pruritic Vulvar Dermatoses1

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2021

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“…It is estimated that 75% of women have been affected by vulvovaginal candidiasis at some point in their lifetime ( 61 , 65 ). Pregnancy, antibiotics, oral contraceptives and hormonal replacement therapies may increase estrogen levels resulting in an increased frequency of disease ( 66 , 67 ). Tamoxifen, an estrogen antagonist in breast tissue, has been reported to have estrogen-like effects on vaginal epithelium in postmenopausal women, increasing risk of vulvovaginal candidiasis ( 68 – 70 ).…”

Section: Pruritic Vulvar Dermatosesmentioning

confidence: 99%

Vulvar Pruritus: A Review of Clinical Associations, Pathophysiology and Therapeutic Management

Raef

Elmariah

2021

Front. Med.

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Vulvar pruritus is an unpleasant sensation and frequent symptom associated with many dermatologic conditions, including infectious, inflammatory and neoplastic dermatoses affecting the female genitalia. It can lead to serious impairment of quality of life, impacting sexual function, relationships, sleep and self-esteem. In this review, common conditions associated with vulvar itch are discussed including atopic and contact dermatitis, lichen sclerosus, psoriasis and infectious vulvovaginitis. We review the potential physiologic, environmental and infectious factors that contribute to the development of vulvar itch and emphasize the importance of addressing their complex interplay when managing this disruptive and challenging symptom.

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