Abstract:Background A gap remains in the role of neoadjuvant therapy for patients with ILC. Method Single-institution retrospective review of patients with ILC who received neoadjuvant therapy between 2008 and 2019. Results 141 patients met inclusion criteria: 71 neoadjuvant chemotherapy (NACT) and 70 neoadjuvant endocrine therapy (NET). 7/71 (9.9%) patients had a pCR following NACT compared to 1/70 (1.4%) with NET ( P = .063). pCR was observed in 5/18 (27.8%) patients with Her2Neu-positive disease following NACT, comp… Show more
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