27Complementary technologies and agricultural practices capable of sustaining profitability to the 28 farmers cultivating BtCotton in India require urgent attention. In India, approval of Btcotton, 29 cultivation of fertilizer-intensive hybrids, higher dose of fertilizer application by farmers, usage 30 of novel pesticides all happened simultaneously during the same period (2002-04) which makes 31 very difficult to identify the individual effect in the yield gain of cotton. In this background, we 32 attempted to understand the proportionate contribution of fertilizers, BT technology and novel 33 group of pesticides in enhancing cotton yield in India. For the analysis, linear regression model 34 and change in partial factor productivity (PFP) of cotton was considered in four different 35 scenarios for yield estimation between 2000 and 2014, i.e. Scenario I: Cotton yield in the 36 absence of technology and enhanced fertilizers usage, Scenario II: Cotton yield only due to 37 enhanced fertilizer usage, Scenario III: Cotton yield with enhanced fertilizer and application of 38 novel pesticides for the insect control, and Scenario IV: Cotton yield due to BT technology, 39 enhanced use of fertilizer, and novel insecticides (actual yield of Cotton in India during Bt 40 phase).Their comparison showed that the individual effect of fertilizers, BT technology and 41 insecticides contributed to 60%, 23% and 17% of cotton yield, respectively in India. Further, 42 18% reduction in PFP was observed recently as compared to 2003-08. Besides, 125 Kg/ha of 43 fertilizers was identified as optimum dose for sustaining high yield in cotton. Thus, present 44 analysis identified the individual effect of different technologies contributing to the yield of 45 cotton in India which can be used in decision making processes for crop improvement. Further, 46 in our opinion, three strategies namely drip fertigation, intercrossing Bt and non-Bt hybrids for 47 resistance management in bollworms, and IPM for sucking pests will primarily drive the research 48 priorities and policy actions for the next 5 to 10 years in sustaining the economic benefits of the 49 six million cotton farmers in India. 50 Keywords 51 Bt cotton, yield trend, fertilizers, pesticides, sucking pests, partial factor productivity 52 53 55 Cotton yield gain story in India is one of the inspiring technological achievements. In 56 India, ~ six million farmers cultivates cotton in an area of about 12 million hectares (2017-18) 57 and approximately 50 million people are either directly or indirectly dependent on cotton for 58 their employment and livelihood. Further, India is the leading producer of cotton in the world.59