Response of Locoregional and Systemic Symptoms to Breast Implant Replacement with Autologous Tissues: Experience in 37 Consecutive Patients

Godfrey, Philip M.; Godfrey, Norman V.

doi:10.1097/00006534-199601000-00018

Cited by 9 publications

(12 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Godfrey et al presented 37 patients with silicone breast implants and complaints such as fatigue, myalgia, arthralgia, hair loss, paresthesia, Raynaud’s phenomenon, dry eyes/mouth, dizziness and headache who underwent replacement of breast implants [33]. Postoperatively, a major improvement in symptoms was observed in 89 % of patients.…”

Section: Resultsmentioning

confidence: 99%

“…Godfrey et al present 37 patients who underwent replacement of breast implants due to systemic complaints and subsequently reconstruction with autologous tissue (TRAM flap or latissimus dorsi flap) [33]. At 6 months postoperatively, only 32.4 % of the patients remained free of symptoms.…”

Section: Resultsmentioning

confidence: 99%

“…However, 7 of 10 patients who improved after explantation also received immunosuppressive or immunomodulatory therapy before, during or after implant removal. In the case series, only one author, Peters [33], closely described the presence of patients with an autoimmune disease in his cohort and whether these patients improved after explantation. None of the 6 patients with well-defined autoimmune disease improved after explantation.…”

Section: Resultsmentioning

confidence: 99%

“…Therefore, patients should also be informed what alternative reconstruction possibilities are available after explantation. Alternatives can consist of reconstruction with autologous tissue such as free flaps (LTP or DIEP flap), lipofilling (with external pre-expansion) or reconstruction with breast implants filled with saline or hydrocellulose [28, 33, 53–55]. In this review, we have found that the effect of reconstruction after explantation in patients with silicone-related complaints has received extremely little attention up until the present time.…”

Section: Discussionmentioning

confidence: 99%

“…Mamma reconstruction with autologous tissue instead of implants tends to be popular in this category of patients due to a higher long-term satisfaction, higher patient’ satisfaction and a higher perception of naturalness [56]. However, in the current reviewed literature, it is not yet clear whether autologous tissue is a good alternative [33]. Reconstruction with a breast implant filled with hydrocellulose might be another alternative since exposure to silicone is diminished [15, 28].…”

Section: Discussionmentioning

confidence: 99%

See 4 more Smart Citations

Is explantation of silicone breast implants useful in patients with complaints?

et al. 2016

View full text Add to dashboard Cite

In this review, we present a critical review of the existing literature reflecting the results of explantation of silicone breast implants in patients with silicone-related complaints and/or autoimmune diseases. A literature search was performed to discuss the following issues: which clinical manifestations and autoimmune diseases improve after explantation, and what is the course of these complaints after explantation. Next, we reviewed studies in which the effect of explantation on laboratory findings observed in patients with silicone breast implants was studied, and lastly, we reviewed studies that described the effect of reconstruction of the breast with a new implant or autologous tissue after explantation. We calculated from the literature that explantation of the silicone breast improved silicone-related complaints in 75 % of the patients (469 of 622). In patients with autoimmune diseases, however, improvement was only infrequently observed without additional therapy with immunosuppressive therapy, i.e., in 16 % of the patients (3 of 18). The effect of explantation did not influence autoantibody testing such as ANA. We discuss several possibilities which could clarify why patients improve after explantation. Firstly, the inflammatory response could be reduced after explantation. Secondly, explantation of the implants may remove a nociceptive stimulus, which may be the causative factor for many complaints. Options for reconstruction of the explanted breast are autologous tissue and/or water-/hydrocellulose-filled breast implant. Unfortunately, in very few studies attention was paid to reconstructive possibilities. Therefore, no adequate conclusion regarding this issue could be drawn. In conclusion, explantation is useful for improvement of silicone-related complaints in 75 % of the patients, whereas in patients who developed autoimmune diseases improvement is only observed when explantation is combined with immunosuppressive therapy. In a patient with silicone-related complaints in which explantation is considered, the patient should be counseled for the different options of reconstruction after explantation.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Is explantation of silicone breast implants useful in patients with complaints?

et al. 2016

View full text Add to dashboard Cite

show abstract

The Prevalence of Self-Reported Health Complaints and Health-Related Quality of Life in Women With Breast Implants

Miseré

Colaris

Tervaert

et al. 2020

Aesthetic Surgery Journal

View full text Add to dashboard Cite

Background Millions of women have silicone breast implants (SBI). Some report a pattern of systemic complaints, also referred to as ASIA syndrome. However, the association between these complaints and breast implants remains uncertain. Objectives This study aimed to evaluate the prevalence of complaints in women with breast implants and healthy controls, and to compare their health-related quality of life (HRQoL). Methods Four groups of subjects were requested to fill in a general and a diagnostic questionnaire, and the Short Form 36. Group 1 was recruited from the Dutch foundation for breast implant illness (BII). Two groups were recruited from Dutch hospitals, where they were augmented or reconstructed with SBI (group 2) or saline-filled and hydrogel implants (group 3). A control group without breast implants was recruited from friends of subjects from group 2 and 3. Results In total, 238 women completed the questionnaires. ASIA manifestations appeared in the majority of the respondents (72.3-98.8%), with a latency period of 0-35 years. Adjusted for age, smoking, and comorbidities, typical symptoms only occurred significantly more frequent in group 1. The presence of a chronic disease was an independent predictor for ASIA syndrome. HRQoL was lower in women with SBI than in women without breast implants. Conclusions The adjusted prevalence of BII manifestations is not significantly higher in women with SBI compared to women without implants. The findings of this study suggest that results on BII are subject to selection bias. Further studies are needed to prove an association between self-reported complaints and SBI.

show abstract

Self-Reported Health Complaints in Women Undergoing Explantation of Breast Implants

Miseré

Hulst

2020

Aesthetic Surgery Journal

View full text Add to dashboard Cite

Background Concerns about the safety of silicone breast implants have existed for years, but a causal relationship between systemic complaints and SBI has not been proven. Nevertheless, women are worried and even request explantation. Objectives This study aimed to review the explantation procedures performed, focusing on patient-reported symptoms preoperatively, the effect of explantation, and the effect of breast reconstruction on these symptoms. Methods A retrospective chart review was performed for patients who had undergone explantation between 2010 and 2020 at Maastricht University Medical Center. Patients excluded were those who had undergone tissue expander (TE) removal, TE to implant exchange, and direct implant exchange. Results More than half of the patients undergoing explantation reported complaints, mostly pain. Some 15% reported suggested implant-related systemic complaints. Breast implant illness (BII) was found to be the fifth most common indication for explantation (11.2%). A history of either allergies or implant rupture resulted in higher odds ratios of having BII (OR=2.1 and 2.1, respectively). Subjective improvement of BII after explantation was reported in about 60%. Conclusions A relatively low prevalence of suggested BII exists among women undergoing explantation; one in nine procedures was performed for this reason. Allergy and implant rupture may increase the likelihood of having BII. About 60% of BII patients experienced an improvement in their complaints after implant removal. Autologous breast reconstruction appears a good alternative. Prospective studies into health complaints and quality of life should be performed to confirm the effectiveness of explantation as a therapy for BII.

show abstract

Response of Locoregional and Systemic Symptoms to Breast Implant Replacement with Autologous Tissues: Experience in 37 Consecutive Patients

Cited by 9 publications

References 1 publication

Is explantation of silicone breast implants useful in patients with complaints?

Is explantation of silicone breast implants useful in patients with complaints?

The Prevalence of Self-Reported Health Complaints and Health-Related Quality of Life in Women With Breast Implants

Self-Reported Health Complaints in Women Undergoing Explantation of Breast Implants

Contact Info

Product

Resources

About