Response- and Progression-Based End Points in Trial and Observational Cohorts of Patients With NSCLC
Yichen Lu,
Spencer S. Langerman,
Emily McCain
et al.
Abstract:ImportanceResponse Evaluation Criteria in Solid Tumors (RECIST) are commonly used to assess therapeutic response in clinical trials but not in routine care; thus, RECIST-based end points are difficult to include in observational studies. Clinician-anchored approaches for measuring clinical response have been validated but not widely compared with clinical trial data, limiting their use as evidence for clinical decision-making.ObjectiveTo compare response- and progression-based end points in clinical trial and … Show more
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