Respiratory viruses seasonality in children under five years of age in Buenos Aires, ArgentinaA five-year analysis

Viegas, Mariana; Barrero, Paola Roxana; Maffey, Alberto; Mistchenko, Alicia

doi:10.1016/j.jinf.2003.10.006

Cited by 77 publications

(89 citation statements)

References 21 publications

(9 reference statements)

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“…variable over several years and this variation is well documented in the worldwide literature [22][23][24] . Based on data obtained in the present study, infection caused by HRV is very frequent and may contribute to increasing the already high demand for healthcare during the influenza season.…”

Section: Financial Support Acknowledgments Conflict Of Interestmentioning

confidence: 84%

Viral etiology among the elderly presenting acute respiratory infection during the influenza season

Watanabe

Carraro

Candeias

et al. 2011

Rev. Soc. Bras. Med. Trop.

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Introduction: Acute respiratory tract infections are the most common illness in all individuals. Rhinoviruses have been reported as the etiology of more than 50% of respiratory tract infections worldwide. The study prospectively evaluated 47 elderly individuals from a group of 384 randomly assigned for acute respiratory viral infections (cold or flu) and assessed the occurrence of human rhinovirus (HRV), influenza A and B, respiratory syncytial virus and metapneumovirus (hMPV) in Botucatu, State of São Paulo, Brazil. Methods: Forty-nine nasal swabs collected from 47 elderly individuals following inclusion visits from 2002 to 2003 were tested by GenScan RT-PCR. HRV-positive samples were sequenced for phylogenetic analysis. Results: No sample was positive for influenza A/B or RSV. HRV was detected in 28.6% (14/47) and hMPV in 2% (1/47). Of 14 positive samples, 9 isolates were successfully sequenced, showing the follow group distribution: 6 group A, 1 group B and 2 group C HRVs. Conclusions: The high incidence of HRV during the months of the influenza season requires further study regarding HRV infection impact on respiratory complications among this population. Infection caused by HRV is very frequent and may contribute to increasing the already high demand for healthcare during the influenza season.

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Section: Financial Support Acknowledgments Conflict Of Interestmentioning

confidence: 84%

Viral etiology among the elderly presenting acute respiratory infection during the influenza season

Watanabe

Carraro

Candeias

et al. 2011

Rev. Soc. Bras. Med. Trop.

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“…About 17,000 samples of nasopharyngeal aspirates were tested by indirect immunofluorescence for respiratory viruses during an active surveillance program of respiratory infections in a public hospital of Buenos Aires from 1999 to 2004 (51,52). A total of 353 of those samples were positive for HRSV and were classified in antigenic group A or B by multiplex nested RT-PCR of the G protein gene, as described by Stockton et al (44).…”

Section: Resultsmentioning

confidence: 99%

“…Nasopharyngeal aspirates were taken in phosphate-buffered saline from children hospitalized in the "Hospital de niños Dr. Ricardo Gutierrez" of Buenos Aires during six consecutive years (1999 to 2004) (51,52). Rapid detection of viral antigens was performed by indirect immunofluorescence with specific antibodies, and the samples were then stored at Ϫ80°C until further analysis.…”

Section: Methodsmentioning

confidence: 99%

Natural History of Human Respiratory Syncytial Virus Inferred from Phylogenetic Analysis of the Attachment (G) Glycoprotein with a 60-Nucleotide Duplication

Trento

Viegas

Galiano

et al. 2006

J Virol

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162

178

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. Phylogenetic analysis indicated that BA sequences with that duplication shared a common ancestor (dated about 1998) with other HRSV G sequences reported worldwide after 1999. The duplicated nucleotide sequence was an exact copy of the preceding 60 nucleotides in early viruses, but both copies of the duplicated segment accumulated nucleotide substitutions in more recent viruses at a rate apparently higher than in other regions of the G protein gene. The evolution of the viruses with the duplicated G segment apparently followed the overall evolutionary pattern previously described for HRSV, and this genotype has replaced other prevailing antigenic group B genotypes in Buenos Aires and other places. Thus, the duplicated segment represents a natural tag that can be used to track the dissemination and evolution of HRSV in an unprecedented setting. We have taken advantage of this situation to reexamine the molecular epidemiology of HRSV and to explore the natural history of this important human pathogen.

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“…Peaks of incidence in the cold and humid months [21,22] Unspecified viral (1-30/% of all diagnoses) and otitis media (1-40%), could be seen as closely related to respiratory tract infections and showed similar seasonal patterns [23] Hypertension Ambulatory blood pressures are higher in the winter [24] For each age, sex, and treatment group systolic and diastolic pressures were higher in winter than in summer.…”

Section: Seasonal Variation Diseasementioning

confidence: 99%

The Variation of Seasonal Diseases in Family Medicine Depends on Infectious Diseases and these are Mainly Respiratory Diseases

Turabián¹

2017

J Gen Pract

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Family medicine is a major source of information about health problems and their variation. For most illnesses the general practitioner is the first point of contact in the health care system and he looks after a population whose age and sex composition is known. He is therefore in an ideal position to conduct inquiries about seasonal variations of diseases. There are diseases where possible patterns of seasonal variation have been established: psychiatric disorders, allergies, heart disease, etc. It has long been accepted that morbidity patterns in general practice vary seasonally, which mainly depends on the acute pathology of infectious origin. In addition, it can be affirmed that respiratory infections represent the most important percentage of infections. So, seasonal variability of diseases in family medicine can be attributed to the variability of respiratory infections. Infectious disease dynamics offer a wide variety of intriguing and unexplained phenomena. There is a gap in how diverse studies encompassing immunology, mathematics, epidemiology, and virology combine to form a complete picture of seasonality. This may be due to the daunting complexity of seasonality itself, which is likely to reflect the actions of a vast multitude of variables. An understanding of what drives seasonal trends may allow: 1) better understanding of transmission dynamics, leading to better methods of prevention, health education, triage, diagnosis and management; 2) generate causal and risk factor hypotheses; 3) awareness of risks and surveillance systems; 4) monitoring the effects of intervention studies such as immunization programs; 5) identifying the specific environmental and socioeconomic factors underlying seasonal transmission; 6) better Interpretation of prevalence or incidence studies; And 7) redistribution of resources for the care of the demand in family medicine and health care system.

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Respiratory viruses seasonality in children under five years of age in Buenos Aires, ArgentinaA five-year analysis

Cited by 77 publications

References 21 publications

Viral etiology among the elderly presenting acute respiratory infection during the influenza season

Viral etiology among the elderly presenting acute respiratory infection during the influenza season

Natural History of Human Respiratory Syncytial Virus Inferred from Phylogenetic Analysis of the Attachment (G) Glycoprotein with a 60-Nucleotide Duplication

The Variation of Seasonal Diseases in Family Medicine Depends on Infectious Diseases and these are Mainly Respiratory Diseases

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