Respiratory tract

Giles, T; McCarthy, Julie M.; Gray, Winifred

doi:10.1016/b978-0-7020-3154-0.00002-8

Cited by 4 publications

(3 citation statements)

References 290 publications

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“…The yeast cells show variable sized diameter ranging from 5 to 25 μ some of which show budding daughter yeast cells attached by a narrow base with a characteristic halo-like thick capsule made of polysaccharides. [ 5 ] The capsule is antiphagocytic and the capsular polysaccharide released in to the tissue initiates immune dysfunction. The cryptococcal polysaccharide is the antigen that is measured as the diagnostic marker of C. neoformans .…”

Section: Discussionmentioning

confidence: 99%

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Disseminated cryptococcosis presenting with generalized lymphadenopathy

Philip

Kaur

Mohan

et al. 2012

J Cytol

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Cryptococcosis is a common opportunistic infection among immunocompromised individuals. Some of the commonly affected sites are respiratory and central nervous system. Lymph node is an unusual site of involvement which could mimic tuberculosis, as seen in our case. We report a 32-year-old male immunocompromised patient presenting with generalized lymphadenopathy who was clinically suspected to have tuberculous lymphadenitis. He was diagnosed to have disseminated cryptococcosis on fine needle aspiration cytology and fungal isolation on culture.

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Section: Discussionmentioning

confidence: 99%

“…Other special stains used to demonstrate the yeast cells are PAS, Gomori's silver methenamine stain and alcian blue. [ 5 ]…”

Section: Discussionmentioning

confidence: 99%

Disseminated cryptococcosis presenting with generalized lymphadenopathy

Philip

Kaur

Mohan

et al. 2012

J Cytol

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“…In sputum smears, isolated CC may be seen in the absence of any tumor formation and are related to several benign entities such as chronic bronchitis, tuberculosis, and a rare genetic disorder named pulmonary alveolar microlithiasis . On the other hand, PB are more frequently related to lung cancer, mostly of the adenocarcinoma type …”

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confidence: 99%

Calcareous concretions and psammoma bodies in sputum smears: Do these similar structures have different clinical significance?

Martínez‐Girón

Martínez-Torre

Tamargo-Peláez

et al. 2014

Diagnostic Cytopathology

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Different noncellular elements, such as round concentric calcified laminated structures, may be found in sputum smears. If these structures appear isolated on the background of the smear, the term usually used to describe them is "calcareous concretions" (CC). On the contrary, when the structures are part of epithelial cell groups or small tissue fragments, the term used to describe them is "Psammoma bodies" (PB). The aim of this work is to establish the relationship between these structures and pulmonary disease, especially lung carcinoma, by searching for the presence of CC and/or PB in sputum smears. Our study has taken as a basis 16.716 sputum smears from 696 patients obtained during a 7-year period (2003-2009). After reviewing them, it was found that from the total, 66 cases (0.39%) contained round calcified structures, 57 of them (0.34%) corresponding to CC, and the remaining 9 ones (0.05%) corresponding to PB. From these 57 CC cases, 56 corresponded to benign entities, and only one was found with lung carcinoma. On the other hand, from the 9 PB cases all of them (100%) were related to lung adenocarcinoma. We conclude that, even having a similar morphological structure, these aforementioned calcified structures we have observed in sputum smears have different and relevant clinical significance.

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