Respiratory Tract

Variations in cancer centers' use of cytology for the diagnosis of small cell lung carcinoma in the National Cancer Data Base

“…[1][2][3][4][5][6][7] Overall 17.3% of patients were diagnosed with cytology. Facility type was strongly and independently associated with cytologic diagnosis (with the highest percentage of cytologic diagnoses by NCIPs and the lowest by CCPs).…”

“…The performance characteristics of these methods in the diagnosis of SCLC have been reported and reviewed elsewhere. 4,5 Although the sensitivities of various types of cytology specimens for lung cancer diagnosis differ somewhat, all have high specificities and high positive predictive values, which are comparable to those of bronchial biopsy, particularly when cytology is interpreted in the context of clinical and imaging findings. 4 Sputum samples for SCLC diagnosis can be obtained with less patient risk and discomfort than other pulmonary cell or tissue samples.…”

“…4,5 Although the sensitivities of various types of cytology specimens for lung cancer diagnosis differ somewhat, all have high specificities and high positive predictive values, which are comparable to those of bronchial biopsy, particularly when cytology is interpreted in the context of clinical and imaging findings. 4 Sputum samples for SCLC diagnosis can be obtained with less patient risk and discomfort than other pulmonary cell or tissue samples. Both tissue and cell samples are usually collected during bronchoscopy performed to investigate endobronchial lesions for suspected malignancy, a practice that has demonstrated the ability to increase diagnostic yield and is cost effective.…”

The pathology associated with putative algal toxicosis in red snapper, Lutjanus species (Bloch 1790)

“…Ingested feed present in stomach and nucleoli (type II pneumocytes) occurs in lungs exposed to toxic insults, and similar cell types are thought to occur in fish lungs and swimbladder (French, 2009;Nelson & Dehn, 2010). The superficial squamous layer of the epidermis of skin was replaced by large cuboidal epithelium in some red snappers (this study), often with clusters of algae wedged in between scale beds (Figure 2f inset).…”

Characterization of Fibrous Mordenite: A First Step for the Evaluation of Its Potential Toxicity

“…D ae influences the deposition depth of inhaled particles in the airways [55]. Particles with D ae > 5 µm are deposited in the nasal respiratory tract, whereas particle with 3 ≤ D ae ≤ 15 µm are deposited in the lower respiratory tract that extends from the trachea to the lungs [43,55,56], which is the main focus of respiratory diseases [57]. Particles with D ae ≈ 2-3 and <0.2 can easily settle in the alveolar space [55].…”