Respiratory symptoms and lung function in a sample of Vermont dairymen and industrial workers.

Babbott, Frank L.; Gump, Dieter W.; Sylwester, David; MacPherson, Bruce R.; Holly, R C

doi:10.2105/ajph.70.3.241

Cited by 37 publications

(17 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In general, airway obstruction and chronic bronchitis has been shown to be associated with working on a farm [5][6][7][8]. Farmers with pulmonary problems may also stop farming.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Long-term outcome of pulmonary function in farmer's lung: a 14 year follow-up with matched controls

Erkinjuntti-Pekkanen

Kokkarinen²,

Tukiainen³

et al. 1997

Eur Respir J

View full text Add to dashboard Cite

The long-term outcome of pulmonary function was evaluated in farmer's lung (FL) patients compared to representative control farmers. This is, to our knowledge, the first such study which has included a control group. Clinical examinations were conducted in 89 FL patients and 84 control farmers, matched by age, sex, and smoking habits. The mean time after the first diagnosed episode of FL was 14 yrs.The mean transfer factor of the lung for carbon monoxide (TL,CO) was on average 12% lower (p<0.001) in FL patients compared to control farmers. In spirometry, the mean maximum expiratory flow at 50% of vital capacity (MEF50) was lower (p=0.08) in FL patients but there were no differences in mean vital capacity (VC) or forced expiratory volume in one second (FEV1) between FL patients and control farmers. However, airway obstruction, defined as an FEV1/VC less than 88% of predicted, was more common in FL patients than in control farmers (33 versus 17%; p=0.02). Patients who had had recurrent episodes of FL had a significantly lower mean TL,CO compared to those FL patients who had experienced only a single episode.In conclusion, impairment of the pulmonary transfer factor is the most important long-term consequence of farmer's lung. However, farmer's lung may also lead to development of airway obstruction.

show abstract

“…In general, airway obstruction and chronic bronchitis has been shown to be associated with working on a farm [5][6][7][8]. Farmers with pulmonary problems may also stop farming.…”

Section: Discussionmentioning

confidence: 99%

“…Farm work in general is known to be a risk factor for chronic bronchitis and impaired pulmonary function [5][6][7][8]. However, no previous study on the long-term outcome of farmer's lung has included healthy farmers as a control group.…”

mentioning

confidence: 99%

Long-term outcome of pulmonary function in farmer's lung: a 14 year follow-up with matched controls

Erkinjuntti-Pekkanen

Kokkarinen²,

Tukiainen³

et al. 1997

Eur Respir J

View full text Add to dashboard Cite

show abstract

“…Gender differences for both HP and seropositivity are likely to represent differences in exposures to offending antigens (16)(17)(18). Despite these methodological limitations, several studies gave consistent results allowing the estimation of the prevalence of farmerÕs lung in exposed farmers from 0.5% to 3% (19)(20)(21)(22)(23)(24).…”

Section: Epidemiologymentioning

confidence: 99%

Hypersensitivity pneumonitis

Girard

and

Cormier

2009

Allergy

112

View full text Add to dashboard Cite

The first few cases of hypersensitivity pneumonitis (HP) were described in the early 20th century in farmers exposed to moldy hay or straw. As then, HP has been ascribed to multiple inhaled antigens found in a large variety of environmental settings. Hypersensitivity pneumonitis results from an exaggerated immune response, which gives rise to acute infection‐like symptoms or to progressive, sometimes irreversible lung damage. The diagnosis is based on a combination of clinical characteristics of the disease. Clinical diagnostic criteria have recently been published. The immune mechanisms leading to HP are still incompletely understood. Initially, believed to be a classes III and IV immune response, we now have a clearer understanding of the complex inflammatory events involved. These include the release of pro inflammatory cytokines and a decrease in the immune control mechanisms via surfactant, dendritic and T‐regulatory cells. Despite the improved understanding, the treatment and outcome of HP have not changed. Oral corticosteroids remain the only effective drugs and contact withdrawal constitutes the ideal solution. If unchecked, HP can lead to irreversible lung damage in the form of fibrosis or emphysema, respiratory insufficiency and even death.

show abstract

“…A n increased risk of chronic bronchitis has been demonstrated in various agricultural groups [1], notably in swine confinement workers [2,3], poultry workers [4,5] and dairy farmers [6][7][8][9]. Several cross-sectional studies have reported lung function impairment in agricultural workers [10,11], including dairy farmers [8,9].…”

mentioning

confidence: 99%

Influence of hay and animal feed exposure on respiratory status: a longitudinal study

Thaon¹,

Thiébaut²,

Jochault³

et al. 2010

Eur Respir J

View full text Add to dashboard Cite

Our aim was to study respiratory symptoms and lung function decline in farmers, with particular attention to the influence of handling hay, straw and animal feed.From a cohort recruited in 1993-1994, 219 (82.6%) dairy farmers, 130 (62.5%) nondairy agricultural workers and 99 (66.4%) controls were re-evaluated in 2006. They answered medical and occupational questionnaires, underwent spirometric tests at both evaluations and pulse oximetry in 2006.Dairy and nondairy agricultural workers showed an increased risk for usual morning phlegm (adjusted OR 4.27 (95% CI 1.41-12.95) and 3.59 (95% CI 1.16-11.10), respectively). Animal feed handling was associated with increased risks of wheezing (p50.01) and usual morning phlegm (p50.04); hay or straw handling was associated with increased risk of wheezing (p50.008). Adjusting for smoking, age, height, sex and altitude, dairy farmers had greater declines in forced expiratory volume in 1 s (FEV1)/forced vital capacity ratio (p50.01) than controls. An increased decline in FEV1 for all agricultural workers was associated with animal feed handling, both measured as a categorical (currently versus never handling; p50.05) or quantitative value (years of exposure during the survey period; p50.03).Hay, straw or animal feed handling represents a risk factor of bronchial symptoms and, for animal feed only, of accelerated decline in expiratory flows.

show abstract

Respiratory symptoms and lung function in a sample of Vermont dairymen and industrial workers.

Cited by 37 publications

References 5 publications

Long-term outcome of pulmonary function in farmer's lung: a 14 year follow-up with matched controls

Long-term outcome of pulmonary function in farmer's lung: a 14 year follow-up with matched controls

Hypersensitivity pneumonitis

Influence of hay and animal feed exposure on respiratory status: a longitudinal study

Contact Info

Product

Resources

About