Respiratory Problems and Substance Misuse

Nanayakkara, Budhima; McNamara, Stephen G.

doi:10.1007/978-3-030-36391-8_74

Cited by 2 publications

(1 citation statement)

References 111 publications

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“…Inhalation of drugs like cocaine and opioids can cause damage to the respiratory tract constituted by e.g. thermal burns (Nanayakkara and McNamara, 2020). Opioids alone (Wang et al, 2021), but also in combination with benzodiazepines (Durkin, 2016) affect the physiologic functions of the respiratory system (Wang et al, 2021).…”

Section: Discussionmentioning

confidence: 99%

Risk of somatic diseases in patients with eating disorders: the role of comorbid substance use disorders

Mellentin

Nielsen

Skøt

et al. 2022

Epidemiol Psychiatr Sci

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Aims Eating disorders (EDs) and substance use disorders (SUDs) often co-occur, and both involve somatic diseases. So far, no study has considered whether comorbid SUDs may impact somatic disease risk in patients with EDs. Therefore, this study aimed to examine the impact of comorbid SUDs on the risk of 11 somatic disease categories in patients with anorexia nervosa (AN), bulimia nervosa (BN) and unspecified eating disorder (USED) compared to matched controls. Methods A retrospective cohort study was conducted using Danish nationwide registries. The study population included 20 759 patients with EDs and 83 036 controls matched on month and year of birth, sex and ethnicity. Hazard ratios (HRs) were calculated to compare the risk of being diagnosed with a somatic disease (within 11 categories defined by the ICD-10) following first ED diagnosis (index date) between ED patients and controls both with and without SUDs (alcohol, cannabis or hard drugs). Results The ED cohort and matched controls were followed for 227 538 and 939 628 person-years, respectively. For ED patients with SUDs, the risk pattern for being diagnosed with different somatic diseases (relative to controls without SUDs) varied according to type of ED and SUD [adjusted HRs ranged from 0.95 (99% CI = 0.57; 1.59) to 4.17 (2.68, 6.47)]. The risk estimates observed among ED patients with SUDs were generally higher than those observed among ED patients without SUDs [adjusted HRs ranged from 1.08 (99% CI = 0.95, 1.22) to 2.56 (2.31, 2.84)]. Abuse of alcohol only had a non-synergistic effect on six disease categories in AN patients and five in BN and USED patients. Abuse of cannabis (with/without alcohol) had a non-synergistic effect on five disease categories in AN and BN patients and two in USED patients. Abuse of hard drugs (with/without alcohol or cannabis) had a non-synergistic effect on nine disease categories in AN patients, eight in BN patients and seven in USED patients. Conclusions The present study documents non-synergistic but not synergistic harmful somatic consequences of SUDs among patients with different EDs, with AN and hard drugs being the most predominant factors. Hence, EDs and SUDs did not interact and result in greater somatic disease risk than that caused by the independent effects. Since EDs and SUDs have independent effects on many somatic diseases, it is important to monitor and treat ED patients for SUD comorbidity to prevent exacerbated physical damage in this vulnerable population.

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Section: Discussionmentioning

confidence: 99%

Risk of somatic diseases in patients with eating disorders: the role of comorbid substance use disorders

Mellentin

Nielsen

Skøt

et al. 2022

Epidemiol Psychiatr Sci

View full text Add to dashboard Cite

show abstract

Intimate partner violence, substance use, and health comorbidities among women: A narrative review

et al. 2023

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Exposure to intimate partner violence (IPV), including physical, sexual, and psychological violence, aggression, and/or stalking, impacts overall health and can have lasting mental and physical health consequences. Substance misuse is common among individuals exposed to IPV, and IPV-exposed women (IPV-EW) are at-risk for transitioning from substance misuse to substance use disorder (SUD) and demonstrate greater SUD symptom severity; this too can have lasting mental and physical health consequences. Moreover, brain injury is highly prevalent in IPV-EW and is also associated with risk of substance misuse and SUD. Substance misuse, mental health diagnoses, and brain injury, which are highly comorbid, can increase risk of revictimization. Determining the interaction between these factors on the health outcomes and quality of life of IPV-EW remains a critical need. This narrative review uses a multidisciplinary perspective to foster further discussion and research in this area by examining how substance use patterns can cloud identification of and treatment for brain injury and IPV. We draw on past research and the knowledge of our multidisciplinary team of researchers to provide recommendations to facilitate access to resources and treatment strategies and highlight intervention strategies capable of addressing the varied and complex needs of IPV-EW.

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Respiratory Problems and Substance Misuse

Cited by 2 publications

References 111 publications

Risk of somatic diseases in patients with eating disorders: the role of comorbid substance use disorders

Risk of somatic diseases in patients with eating disorders: the role of comorbid substance use disorders

Intimate partner violence, substance use, and health comorbidities among women: A narrative review

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