Respiratory Impairment Related To Vaping

Abstract

The use of electronic cigarettes referred to as “vaping” have a detrimental impact on human health, especially on the respiratory system. Depending on the chemical composition and the frequency and quantity of inhalation exposure, the severity of the symptoms may vary among patients. Here we discuss the main potential triggers for EVALI (e-cigarette or vaping product use-associated lung injury). Some vaping-related cellular response mechanisms, including inflammatory response and oxidative stress, and a correlation between vaping and the susceptibility to respiratory infections (including SARS-CoV-2), are presented. In-depth, long-term studies, especially involving cellular responses, are necessary to fully elucidate the process leading to the onset of EVALI symptoms.