Respiratory gated [18F]FDG PET/CT for target volume delineation in stereotactic radiation treatment of liver metastases

Bundschuh, Ralph A.; Andratschke, Nicolaus; Dinges, Julia; Duma, Marciana Nona; Astner, Sabrina T.; Brügel, Melanie; Ziegler, Sibylle; Molls, M.; Schwaiger, Markus; Essler, Markus

doi:10.1007/s00066-012-0094-3

Cited by 37 publications

(21 citation statements)

References 24 publications

(34 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Multi-modality imaging techniques including MRI and PET/CT have been used for SBRT of liver metastases (3,4). PET/CT imaging provides biologic information on the tumor and has proved useful for staging, surveillance, and radiation treatment planning.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The utility of positron emission tomography/computed tomography in target delineation for stereotactic body radiotherapy for liver metastasis from primary gastric cancer: an illustrative case report and literature review

Lewis¹,

Chiang²,

Butler³

et al. 2017

J. Gastrointest. Oncol.

View full text Add to dashboard Cite

Abstract:The liver is a common site for metastatic disease for many cancers. Radiation therapy is one means of treatment for liver metastases, especially for patients unable to undergo surgery or ineligible for systemic chemotherapy. In particular, stereotactic body radiotherapy (SBRT) has become an important option in the treatment of metastatic disease in the liver. SBRT delivers ablative doses of radiation in relatively few fractions. As such, precise and clear imaging plays an important role in maximizing disease control while minimizing normal tissue toxicity. We present a case that highlights the importance of using multiple imaging modalities for target volume delineation in stereotactic radiation treatment of liver metastases.

show abstract

Section: Discussionmentioning

confidence: 99%

“…As a result, utilization of PET/CT imaging may improve target delineation for liver metastases compared to MRI (4). In addition, two planning studies have suggested that 4D PET/CT may provide added benefit for liver SBRT planning and target delineation compared to non-gated PET/CT imaging (4,11).…”

Section: Discussionmentioning

confidence: 99%

The utility of positron emission tomography/computed tomography in target delineation for stereotactic body radiotherapy for liver metastasis from primary gastric cancer: an illustrative case report and literature review

Lewis¹,

Chiang²,

Butler³

et al. 2017

J. Gastrointest. Oncol.

View full text Add to dashboard Cite

show abstract

“…The value of anatomic-biologic tumor targeting achieved with PET/CT in the radiotherapy planning process has been clearly defined in lung, head, and neck malignancies as well as lymphoid neoplasms (8)(9)(10). Published data also suggest improvements in the imaging of esophageal, cervical, and rectal cancers (21,22).…”

Section: Discussionmentioning

confidence: 99%

Is there any impact of PET/CT on radiotherapy planning in rectalcancer patients undergoing preoperative IMRT?

Kılıç¹,

Çatlı²,

Ülger³

et al. 2015

Turk J Med Sci

View full text Add to dashboard Cite

Background/aim: To investigate the effect of positron emission tomography-computed tomography (PET/CT)-based contouring on dosimetric parameters in rectal cancer patients undergoing preoperative intensity-modulated radiation therapy (IMRT). Materials and methods:Preoperative radiation therapy plans with conformal radiotherapy (CRT) or IMRT were created and examined according to the CT-and PET/CT-based contouring of 20 rectal cancer patients, retrospectively. Results:The target volumes delineated with PET/CT were significantly larger than the volumes created by CT (P = 0.043). Dose delivered to 98% of the planning target volume was high in IMRT planning contouring with CT and PET/CT compared with CRT planning, but the difference was not statistically significant (P = 0.056). Percent volumes receiving 105% of dose and 110% of dose were low in IMRT planning when compared with CRT (P < 0.0001 and P = 0.044, respectively). The volumes receiving 45 Gy for the small intestine, femur heads, and bladder and the maximum dose received by the bladder were significantly lower in IMRT. Conclusion:We showed that the target volumes created with PET/CT are significantly larger than the target volumes created with CT and that IMRT provides lower radiation exposure to the tumor-free tissues compared to the CRT planning. The dosimetric results primarily favor IMRT planning in rectal cancer patients and consequently present the significant alteration in target volumes.

show abstract

“…Thus, application of even high tumoricidal doses can be applied safely and non-invasively by stereotactic body radiotherapy (SBRT), intensity-modulated RT (IMRT) or even particle beam therapy (PBT) [11][12][13][14][15][16][17][18][19][20][21]. Many reports over the last years have shown favourable local control rates after radiosurgery or hypofractionated RT in liver metastases or even small primary liver tumors with an advantageous toxicity profile [22][23][24][25][26][27][28][29].…”

Section: Introductionmentioning

confidence: 99%

Single-dose radiosurgical treatment for hepatic metastases – Therapeutic outcome of 178 treated lesions from a single institution

Habermehl¹,

Herfarth²,

Bermejo³

et al. 2013

Z Gastroenterol

View full text Add to dashboard Cite

Background: Local ablative therapies such as stereotactically guided single-dose radiotherapy or helical intensitymodulated radiotherapy (tomotherapy) with high single-doses are successfully applied in many centers in patients with liver metastasis not suitable for surgical resection. This study presents results from more than 10 years of clinical experience and evaluates long-term outcome and efficacy of this therapeutic approach.

show abstract

Respiratory gated [18F]FDG PET/CT for target volume delineation in stereotactic radiation treatment of liver metastases

Cited by 37 publications

References 24 publications

The utility of positron emission tomography/computed tomography in target delineation for stereotactic body radiotherapy for liver metastasis from primary gastric cancer: an illustrative case report and literature review

The utility of positron emission tomography/computed tomography in target delineation for stereotactic body radiotherapy for liver metastasis from primary gastric cancer: an illustrative case report and literature review

Is there any impact of PET/CT on radiotherapy planning in rectalcancer patients undergoing preoperative IMRT?

Single-dose radiosurgical treatment for hepatic metastases – Therapeutic outcome of 178 treated lesions from a single institution

Contact Info

Product

Resources

About