IntroductionIn areas where the disease is not endemic and the flocks on neighbouring farms are well separated, the most satisfactory method of controlling infectious laryngotracheitis is to dispose of all survivor stock, clean and disinfect the premises and after a period of at least a month restock with uninfected chickens. Such a method was first advocated by GIBBS in 1933. Where the disease is endemic and the poultry flocks on neighbouring farms are within a few hundred yards of each other reinfection commonly occurs and vaccination is the best means of control. BEAUDETTE (1949) and SEDDON (1952) reviewed the control of the disease in the U.S.A. and Australia, respectively, and it is in these two countries that most of the recent research into the control of the disease by vaccination has been undertaken. Thus, in America, BENTON, COVER and GREENE (1958) have shown that a relatively mild virus administered by intranasal drop produces immunity which, at least for a short period, is comparable with that produced by cloacal scarification. HITCHNER and WINTERFIELD (1960) showed that one vaccination by cloacal scarification does not always produce a durable immunity and that revaccination is advisable, for which they advocate the conjunctival drop method. SHIBLEY, LUGINBUHL and HELMBOLT (1963) produced immunity in seven-day-old cockerels by intraconjunctival drop. I n Australia,