Respiratory Difficulty Following Bismuth Subgallate Aspiration

Murray, Alan D.; Gibbs, Scott R.; Billings, Kathleen R.; Biavati, Michael J.

doi:10.1001/archotol.126.1.79

Cited by 10 publications

(5 citation statements)

References 9 publications

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“…As an additional complication, respiratory distress has been reported due to bismuth subgallate when used to control hemostasis during tonsillectomy and adenoidectomy [21].…”

Section: Discussionmentioning

confidence: 99%

Reversible nephrotoxicity after overdose of colloidal bismuth subcitrate

İşlek

Uysal

Gök

et al. 2001

Pediatric Nephrology

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Although toxicity due to acute and chronic use of bismuth salts is well known, nephrotoxicity after ingestion of colloidal bismuth has been reported in few cases so far. Here we report the first case of acute renal failure (ARF) due to colloidal bismuth subcitrate overdosage in childhood. A 2-year-old boy was admitted to the hospital 6 h after ingestion of 28 De-Nol tablets (colloidal bismuth subcitrate 8.4 g). On admission, physical examination was unremarkable and he showed no signs of encephalopathy. Initially gastric lavage was performed then appropriate fluid therapy was started. ARF associated with uremia and oliguria developed on day 2 and peritoneal dialysis therapy was prescribed on day 4 for 10 days. Blood and urine bismuth levels were 739 micrograms/l and 693 micrograms/l, respectively, 10 days after the pills had been taken. His urine volume gradually increased and plasma BUN and creatinine levels decreased during peritoneal dialysis. On day 20 post-admission, plasma BUN and creatinine were 14 mg/dl and 0.7 mg/dl, respectively. Blood bismuth levels were 96 micrograms/l on day 60 and 12 micrograms/l on day 105. Now the patient is well and has no problem. This case suggests that ARF may develop in children following colloidal bismuth subcitrate overdosage; the prognosis is good, and peritoneal dialysis may be useful in these cases.

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“…As an additional complication, respiratory distress has been reported due to bismuth subgallate when used to control hemostasis during tonsillectomy and adenoidectomy [21].…”

Section: Discussionmentioning

confidence: 99%

Reversible nephrotoxicity after overdose of colloidal bismuth subcitrate

İşlek

Uysal

Gök

et al. 2001

Pediatric Nephrology

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“…In terms of BIPP-related complications, direct bismuth aspiration has been reported 35 to cause pulmonary complications in laboratory animals, but no clinical correlation in humans had been previously described until Murray et al 35 reported two pediatric cases of bismuth aspiration leading to respiratory difficulties after tonsillectomy and adenoidectomy; neither child's respiratory condition necessitated airway intubation. With that in mind, the application of BIPP, like all topical medications, must be performed with caution and following proper guidelines to minimize potential risks.…”

Section: Evaluation Of Wound Healingmentioning

confidence: 99%

Posttonsillectomy Pain Relief and Wound Healing by Applying Bismuth Iodoform Paraffin Paste (BIPP) to Dissected Tonsillar Beds

Idris,

Ramli,

Yaacob

et al. 2024

Int Arch Otorhinolaryngol

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Introduction Tonsillectomy is one of the most common operations performed by otorhinolaryngology surgeons worldwide; however, the insufficient quality of the postoperative pain management and effective posttonsillectomy pain relief remain a clinical dilemma. Objective To evaluate the efficacy of applying bismuth iodine paraffin paste (BIPP) to the dissected fossa as an adjuvant therapy for a better outcome in terms of posttonsillectomy pain management and due to its wound healing properties. Methods The present is a prospective randomized control pilot study with 44 patients aged > 7 years who underwent tonsillectomy. The patients were divided into two groups: the control group and the group that had BIPP applied to the dissected tonsillar fossa. The visual analogue scale score and the post-onsillectomy percentage of tonsillar fossa epithelization were recorded and evaluated. Results Both subjectively and objectively, there a was statistically significant pain-relieving effect in the BIPP group within the first 5 postoperative days (p < 0.05). From postoperative day 3 onward, the dissected area of the tonsillar fossa healed significantly faster in the BIPP group compared with the control group, and it became stable on day 14. Conclusion The topical application of BIPP showed a better pain-relieving effect, it was safe, and hastened wound healing after tonsillectomy.

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“…In the United States, BSG is an active ingredient in Devrom® (internal deodorant), an over-the-counter FDA-approved medicine [62]. The side effects of BSG include temporary darkening of the tongue and risk of foreign body response that may result in acute pneumonia [157, 164]. Due to BSG’s possible hypersensitivity to the substance, hepatic or renal impairment is the caution impeding its application in patients with liver or kidney disease [157].…”

Section: Main Text: Topical Biomaterials Used For Pthmentioning

confidence: 99%

Topical biomaterials to prevent post-tonsillectomy hemorrhage

Liu

Rodman

Worobetz

et al. 2019

J of Otolaryngol - Head & Neck Surg

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Despite advances in surgical technique, postoperative hemorrhage remains a common cause of mortality and morbidity for patients following tonsillectomy. Application of biomaterials at the time of tonsillectomy can potentially accelerate mucosal wound healing and eliminate the risk of post-tonsillectomy hemorrhage (PTH). To understand the current state and identify possible routes for the development of the ideal biomaterials to prevent PTH, topical biomaterials for eliminating the risk of PTH were reviewed. Alternative topical biomaterials that hold the potential to reduce the risk of PTH were also summarized.

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Respiratory Difficulty Following Bismuth Subgallate Aspiration

Cited by 10 publications

References 9 publications

Reversible nephrotoxicity after overdose of colloidal bismuth subcitrate

Reversible nephrotoxicity after overdose of colloidal bismuth subcitrate

Posttonsillectomy Pain Relief and Wound Healing by Applying Bismuth Iodoform Paraffin Paste (BIPP) to Dissected Tonsillar Beds

Topical biomaterials to prevent post-tonsillectomy hemorrhage

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