Resorbable polymers for internal fixation

Soft tissue and cancellous bone reaction to the implantation of novel biodegradable pins and plates in rabbits

“…To be biocompatible, they should have no adverse effects on the implant recipient by inducing adverse inflammatory reactions and not being carcinogenic, teratogenic, or toxic (Gogolewski 1992). Similarly, they must be reproducibly processed into desired form and sterilized without being degraded.…”

Nanofibrous Scaffolds of Bio-Polyesters: In Vitro and In Vivo Characterizations and Tissue Response

“…This means that the degradation of nanofibrous scaffolds progresses preferentially from the surface of the nanofibrous scaffolds or interface which contacts with the tissues of rat. It is deduced that some substance such as tissue enzymes facilitate the degradation (Gogolewski, 1992). After 4 weeks of implantation, the PLLA nanofibrous scaffold showed 28% decrease in crystallinity (86% to 58%) while the electrospun stereocomplexed PLA scaffold showed 12% decrease in crystallinity (61% to 49%) (Fig.…”

The use of a resorbable augmentation device to secure plating of osteoporotic bones

“…Medullary augmentation devices (10 × 120 mm) were meltextruded from poly(L-lactide) (PLLA) [3,4,9,10,17]. The PMMA used cement was Palacos (Essex Chemie AG, Lucerne).…”