Resonance-driven ion transport and selectivity in prokaryotic ion channels

Abstract

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Antiresonant driven systems for particle manipulation

“…The results obtained broaden the understanding of the resonant phenomena in drift-diffusion systems and may provide the rational for the interpretation of dataset existing in the literature [18,37,50,51]. The existence of the new regimes we have found, in which resonances and antiresonances coexist, opens up the possibility of designing the driving force to be able to control the flow of particles and to manipulate nano-objects in order to study their properties.…”

“…Such a scenario can be realized by means of optical, electric or magnetic fields [17][18][19] or by forces resulting from the geometrical confinement of the particles. This is the case of the ondulatory motion of worm-like organisms [20,21], peristaltic pumping [22][23][24][25], fluctuating ion channels and pores [26][27][28][29][30][31][32][33][34][35][36][37] as well as synthetic soft micro-nanofluidic devices [38][39][40]. Knowing what the impact of higher order harmonics is on the response of the system is a question of great current interest.…”

Cumulative hydropathic topology of a voltage‐gated sodium channel at atomic resolution

“…S8). The importance of the topological interplay between hydropathic “sinks” and “sources” in ion permeation dynamics and, specifically, ion selectivity was recently highlighted in Reference 49. Similar to the previous section, we introduced the expression that incorporates topological information extracted from every molecular scale l α ( p ) where Γ (1) ( α ) represents the set of all detected dipole centers for a given scaling index α (see section 2).…”

Quantum coherence on selectivity and transport of ion channels

“…This rapid and high selectivity is critical for the physiology of living creatures. Various ion channels are involved in several biological processes, including nerve signaling, muscular contraction, cellular homeostasis, and epithelial fluid transport 18 – 20 . The selectivity of ion channels refers to the fact that each ion channel is individually for passing the specific ions.…”

“…The selectivity of ion channels refers to the fact that each ion channel is individually for passing the specific ions. For example, potassium channels only allow the potassium ions to pass through the membrane while rejecting the other ions (e.g., sodium ions) 18 . The ion radii of sodium and potassium ions only differ by 0.38 A.…”