Resolving crossing fibres using constrained spherical deconvolution: Validation using diffusion-weighted imaging phantom data

Tournier, Jacques‐Donald; Yeh, Chun‐Hung; Calamante, Fernando; Cho, Kuan-Hung; Connelly, Alan; Lin, Ching-Po

doi:10.1016/j.neuroimage.2008.05.002

Cited by 551 publications

(498 citation statements)

References 26 publications

Supporting

Mentioning

487

Contrasting

Unclassified

Order By: Relevance

“…A probabilistic streamlines method (SD_PROB) was employed in combination with the constrained spherical deconvolution (CSD) technique to model multiple fibre orientations (Tournier et al, 2007). The maximum harmonic order (lmax) used in this study was lmax = 6 (Tournier et al, 2004;Tournier et al, 2008). Details of fibre tracking analysis: (i) Whole brain fibre tracking for super-resolution TDI mapping: randomly seeded throughout the brain.…”

Section: Fibre Tracking Mrimentioning

confidence: 99%

Mapping somatosensory connectivity in adult mice using diffusion MRI tractography and super-resolution track density imaging

et al. 2014

Self Cite

View full text Add to dashboard Cite

Section: Fibre Tracking Mrimentioning

confidence: 99%

Mapping somatosensory connectivity in adult mice using diffusion MRI tractography and super-resolution track density imaging

et al. 2014

Self Cite

View full text Add to dashboard Cite

“…seed points were randomly defined in continuous space covering the whole brain or phantom) using the following relevant parameters: 1 mm step-size, maximum angle between steps = 45º, 3 FOD samples/step, any track with length < 10 mm (for the in vivo data) or < 4 mm (for the in silico data) was discarded, termination criteria: exit the brain (or the numerical phantom) or when the CSD fibre-orientation distribution amplitude was < 0.1. The primary parameter of interest in CSD is the maximum harmonic order lmax (which determines the 'sharpness' of the fibre orientation distributions) (Tournier et al, 2004;Tournier et al, 2007;Tournier et al, 2008); lmax = 10 (for the in vivo data) and 8 (for the in silico data) were employed in this study.…”

Section: Fibre-trackingmentioning

confidence: 99%

Track density imaging (TDI): Validation of super resolution property

et al. 2011

Self Cite

View full text Add to dashboard Cite

“…In this work, we study the cerebellar peduncle pathways in a population of pediatric and young adult subject, with normal brain MRI reports, using high‐angular resolution diffusion imaging (HARDI) (Tournier et al., 2008; Tuch et al., 2002). Our aim is to improve the knowledge of development of these pathways and to create an initial framework for future studies of normal and pathologic development of these tracts.…”

Section: Introductionmentioning

confidence: 99%

High‐angular resolution diffusion imaging tractography of cerebellar pathways from newborns to young adults

Levman

Lim

et al. 2016

Brain and Behavior

View full text Add to dashboard Cite

IntroductionMany neurologic and psychiatric disorders are thought to be due to, or result in, developmental errors in neuronal cerebellar connectivity. In this connectivity analysis, we studied the developmental time‐course of cerebellar peduncle pathways in pediatric and young adult subjects.MethodsA cohort of 80 subjects, newborns to young adults, was studied on a 3T MR system with 30 diffusion‐weighted measurements with high‐angular resolution diffusion imaging (HARDI) tractography.ResultsQualitative and quantitative results were analyzed for age‐based variation. In subjects of all ages, the superior cerebellar peduncle pathway (SCP) and two distinct subpathways of the middle cerebellar peduncle (MCP), as described in previous ex vivo studies, were identified in vivo with this technique: pathways between the rostral pons and inferior‐lateral cerebellum (MCP cog), associated predominantly with higher cognitive function, and pathways between the caudal pons and superior‐medial cerebellum (MCP mot), associated predominantly with motor function.DiscussionOur findings showed that the inferior cerebellar peduncle pathway (ICP), involved primarily in proprioception and balance appears to have a later onset followed by more rapid development than that exhibited in other tracts. We hope that this study may provide an initial point of reference for future studies of normal and pathologic development of cerebellar connectivity.

show abstract

Resolving crossing fibres using constrained spherical deconvolution: Validation using diffusion-weighted imaging phantom data

Cited by 551 publications

References 26 publications

Mapping somatosensory connectivity in adult mice using diffusion MRI tractography and super-resolution track density imaging

Mapping somatosensory connectivity in adult mice using diffusion MRI tractography and super-resolution track density imaging

Track density imaging (TDI): Validation of super resolution property

High‐angular resolution diffusion imaging tractography of cerebellar pathways from newborns to young adults

Contact Info

Product

Resources

About