Resolved genomes of wastewater ESBL-producing
Escherichia coli
and metagenomic analysis of source wastewater samples
Clinton Cheney,
Jared D. Johnson,
John P. Ste. Marie
et al.
Abstract:Extended-spectrum beta-lactamase (ESBL)-producing
Escherichia coli
pose a serious threat to human health because of their resistance to the most commonly prescribed antibiotics: penicillins and cephalosporins. In this study, we provide a genomic and metagenomic context for the determinant beta-lactam resistance genes of ESBL-positive
E. coli
isolated from various wastewater treatment utilities in Oregon, USA. Class A beta-lactamase genes on chromosomes (
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