Resolution of Post-Molar Pregnancy Uterine Arteriovenous Malformation Following Treatment with GnRH Agonist Concomitantly with an Aromatase Inhibitor and Tranexamic Acid

Abstract

Background: Acquired uterine arteriovenous malformations (AVM) are a rare but potentially serious condition that can result in severe bleeding. Rarely, uterine AVM can occur following a complete molar pregnancy. Resolution of AVMs has been reported recently with conservative management using a combination of Gonadotropin-Releasing Hormone (GnRH) agonist, an aromatase inhibitor and tranexamic acid. This treatment has not previously been reported in a patient with AVM post molar gestation. Case Presentation: A 23-year-old woman was diagnosed with a large uterine arteriovenous malformation following a suction curettage for a molar pregnancy. Complete resolution of the lesion on imaging was seen after six weeks of medical management. Conclusion: A uterine arteriovenous malformation can develop in a patient post complete molar pregnancy and can be successfully treated with medical management.