Resolution of Othello-like syndrome following ventricular shunting in a post traumatic normal pressure hydrocephalus subject

Pinto, Fernando; Stump, Gabriela; Valiengo, Leandro; Oliveira, Matheus Fernandes de

doi:10.1590/0101-60830000000098

Cited by 1 publication

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“…Foreign scholars have reported 2 cases of mild head trauma patients with PTH caused by midbrain actual obstruction, which was later confirmed by neuroendoscopy to be caused by the new diaphragm, but the experience of this rare case deserves clinical attention. It is traditionally believed that CSF is reabsorbed through arachnoid granulations and that multiple craniotomy procedures are at greater risk of such obstruction (5). Intracranial infection after TBI will further aggravate brain tissue adhesion, resulting in aggravation of cerebrospinal fluid outflow channel obstruction.…”

Section: Introductionmentioning

confidence: 99%

Study of Compound Sanqi Nanoparticles for Local Infection of Hydrocephalus Patients after Neurosurgery Medium Craniocerebral Injury

Ni¹,

Wu²,

Wu³

et al. 2022

Cell Mol Biol (Noisy-le-grand)

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Panax notoginseng is the dried root and rhizome of Panax notoginseng, which has the effect of lowering blood lipid, lowering blood pressure and promoting blood circulation to remove blood stasis. At present, the research on Panax notoginseng is mainly focused on its pharmacological action and its compound preparation, but the research on the granule of Panax notoginseng is less. This paper mainly studied the clinical study of compound notoginseng nanoparticles in the treatment of local infection in patients with hydrocephalus after medium craniocerebral injury in neurosurgery. The purpose of this article is to investigate the effects of compound notoginseng nanoparticles on serum TNF-α, IL-2 and IL-6 in rats with craniocerebral injury and to verify the protective effect of compound notoginseng nanoparticles on the body after craniocerebral injury. In this paper, 90 patients admitted to a hospital in this city were divided into a control group, model group and compound notoginseng nanoparticle group. According to the Zealonga method, the neurological function deficit score of experimental rats in each group was evaluated. The levels of TNF-α, IL-2 and IL-6 in the serum of the three groups were observed 1, 3 and 5 days after treatment. RESULTS: Compared with serum TNF-α, IL-2 and IL-6 of the three groups, there were significant differences in the main effects of time and intervention (P < 0.05). CONCLUSIONS: Compound notoginseng nanoparticles can reduce the contents of TNF-α and IL-6 in serum and increase the expression of IL-2 in rats with craniocerebral injury.

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Section: Introductionmentioning

confidence: 99%