Resolution of N-methylamphetamine enantiomers with tartaric acid derivatives by supercritical fluid extraction

Enantioselective extraction of d,l-tryptophan by a new chiral selector: Complex formation with di(2-ethylhexyl)phosphoric acid and O,O′-dibenzoyl-(2R,3R)-tartaric acid

“…1) has been known as a chiral selector of enantiomers, such as ephedrine, chiral alcohols [10] and N-methylamphetamine [11]. Moreover, it was also observed DBTA can form complexes with some alcohols and anilides.…”

Intercalation of Mg–Al layered double hydroxides by (+)-dibenzoyl-d-tartaric acid: Preparation and characterization

“…Some research efforts have been denoted to tartrate intercalated LDHs [15][16][17][18][19]. (+)-Dibenzoyl-D-tartaric acid (DBTA), a derivative of D-tartaric acid, has been known as a chiral selector of enantiomers, such as ephedrine, chiral alcohols [20], N-methylamphetamine [21] and amino acids [22]. The intercalation of DBTA in the confined interlayer region of LDHs should give rise to a new type of stationary phase for liquid chromatography with high chiral selectivity and low degree of leaching [23].…”

Crystal structure of (S)-sec-butylammonium L-tartrate monohydrate

“…This method has been used for the resolution of amine enantiomers by protonation with chiral tartaric acid to produce diastereomeric salts. Examples include resolution of -phenylethylamine (Ault 1965;Kokila et al, 2002), N-methylamphetamines (Kmecz et al, 2004), 2-(benzylamino)-4-oxo-4-phenylbutanoate (Berkeš et al, 2003), 3-aminobutanol (Yatcherla et al, 2015), aminonaphthols (Periasamy et al, 2009), and serotonin and dopamine antagonists (Campiani et al, 2002).…”