Resolution of blue minocycline pigmentation of the face after fractional photothermolysis

“…Ein Ansprechen der erapie wurde bei vier von fünf Patienten mit klinischen Verbesserungen von 50 % und mehr berichtet [11,37,43,44]. Ähnlich gute Ergebnisse nden sich auf asiatischer Haut mit erweiterten Poren [9,45,46,47], wobei das Gesamtbild wahrscheinlich den Haupteindruck vermittelt [48]. Zudem können Narben, die durch andere Interventionen mit Laser oder Licht entstanden sind, therapiert werden [10] sowie hypopigmentierte Narben [49], hypertrophe Narben [50], Verbrennungsnarben [51] und atrophe Narben [52].…”

Section: Narbenunclassified

Fraktionierte nicht ablative Laser

Paasch¹

2015

ästhet dermatol kosmetol

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Minimalinvasive Systeme wie der nicht ablativ fraktionierte Laser werden zunehmend für die Therapie der chronisch lichtgeschädigten Haut sowie von Narben und weiteren Indikationen interessant. Derzeit werden die Laser am häufigsten zur Therapie von Falten und Narben eingesetzt. 2 Die chronisch lichtgealterte Haut ist gekennzeichnet durch eine Ab achung der Reteleisten, Pigmentverschiebungen, weiten Gefäßen sowie verdickten, fragmentierten und amorphen kollagenen Fasern. cme fortbildung 37 03 • 2015 ästhetische dermatologie

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“…[74] The pigmentation may persist for years even after stopping therapy. Clearance was achieved using quality switched lasers: the Q-switched-Nd:YAG laser, [75] Q-switched ruby laser, [76][77][78] Q-switched-alexandrite laser, [79,80] and fractionated photothermolysis (Fraxel model; Reliant, Mountain View, CA, USA); [81] as well as with oral isotretinoin alone. [82] …”

Section: Pigmentationmentioning

confidence: 99%

Minocycline in Acne Vulgaris

Ochsendorf

2010

American Journal of Clinical Dermatology

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Minocycline is a semi-synthetic, second-generation tetracycline. It was introduced in 1972 and has both antibacterial and anti-inflammatory properties. Minocycline is used for a variety of infectious diseases and in acne. Even today, new indications beyond the antibacterial indications are being investigated such as its use in neurologic diseases. Formerly, minocycline was thought to have a superior efficacy in the treatment of inflammatory acne, especially with respect to antibacterial-resistant Propionibacterium acnes. A thorough review of the literature, however, shows that minocycline is not more effective in acne than other tetracyclines. Compared with first-generation tetracyclines, minocycline has a better pharmacokinetic profile, and compared with doxycycline it is not phototoxic. However, minocycline has an increased risk of severe adverse effects compared with other tetracyclines. It may induce hypersensitivity reactions affecting the liver, lung, kidneys, or multiple organs (Drug Reaction with Eosinophilia and Systemic Symptoms [DRESS] syndrome) in the first weeks of treatment and, with long-term treatment, may cause autoimmune reactions (systemic lupus erythematosus, autoimmune hepatitis). In addition, CNS symptoms, such as dizziness, are more frequent compared with other tetracyclines. Long-term treatment may induce hyperpigmentation of the skin or other organs. Resistance of P. acnes to minocycline also occurs, dependent on the prescribing behavior. Considering the aspects of efficacy, its adverse effect profile, resistance, price, and alternatives, minocycline is no longer considered the first-line antibacterial in the treatment of acne.

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Resolution of blue minocycline pigmentation of the face after fractional photothermolysis

Cited by 43 publications

References 18 publications

Minocycline-Induced Hyperpigmentation

Minocycline-Induced Hyperpigmentation

Fraktionierte nicht ablative Laser

Minocycline in Acne Vulgaris

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