Resolution of Biparametric Mixtures Using Bead Injection Spectroscopic Flow-through Renewable Surface Sensors

Ruedas-Rama, María J.; Ruiz-Medina, A.; Molina‐Díaz, Antonio

doi:10.2116/analsci.21.1079

Cited by 17 publications

(20 citation statements)

References 28 publications

(13 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…After each analysis, the rod is pulled back far enough to open the outlet and let the used beads flow out. Commercially available flow-through cells commonly used in FI liquid-phase spectrophotometric detection have been adapted to BI spectroscopy by Molina-Díaz and coworkers [18][19][20]. Glass wool is used to plug the outlet of the flow cell to keep beads inside.…”

Section: Fi-bi With Home Made and Commercial Flow Cellsmentioning

confidence: 99%

“…Bead discarding is done by backward flushing the beads out with a high flow rate solution using an ancillary uni-directional peristaltic pump. Two Hellma-type flow cells, namely, 138 OS (1 mm light path, 50 µL inner volume) and 176 QS (1.5 mm light path, 25 µL inner volume), were used for spectrophotometric [18,20] and fluorometric [19] optosensing, respectively. The configurations of both flow cells can be found in Hellma's cell catalog and works published by Molina Diaz's group [18][19][20].…”

Section: Fi-bi With Home Made and Commercial Flow Cellsmentioning

confidence: 99%

“…For environmental assays of trace metals, custom-made beads have been loaded with ligands (e.g., carbazides or azo compounds) in an off-line fashion [28,29,30] because the time frame for quantitative impregnation of the bead surface then can be selected at will regardless of ligand sorption kinetics. As compared with on-line protocols, higher reagent concentration on the sorbent material is then ensured, which in turn should lead to improved enrichment factors and analyte breakthrough volumes.…”

Section: Analytical Procedures For Bead Injection 51 Bead Modificationmentioning

confidence: 99%

“…This reaction might lead to improved retention selectivity and increased affinity of the analyte to the sorptive material. For example, trace metals after derivatization into a non-charged chelate or (co)precipitate are selectively sorbed on reversed-phase (e.g., PTFE or octadecyl-chemically modified copolymer) packing materials [18,36,37]. Indirect determination of drugs, e.g., promethazine and trifluoperazine, could be effected by on-line oxidation with Fe(III) with the subsequent complexation of the resulting Fe(II) with ferrozine followed by solid-phase spectrophotometric detection of the chelate onto anion-exchangers [18].…”

Section: Analyte Uptakementioning

confidence: 99%

“…Though most frequently used in combination with spectrophotometry [9,15,17,20,24,25,35], BI spectroscopy has been also found applications involving fluorometric [12,19] and chemiluminescence [22,23] detection. The most important requirement for BI spectrophotometry is the optical transparency of beads to prevent high signal background and light scattering effects.…”

Section: Detection Techniquesmentioning

confidence: 99%

See 4 more Smart Citations

Recent developments in automatic solid-phase extraction with renewable surfaces exploiting flow-based approaches

Miró

Hartwell

Jakmunee

et al. 2008

TrAC Trends in Analytical Chemistry

View full text Add to dashboard Cite

. (2008). Recent developments in automatic solid-phase extraction with renewable surfaces exploiting flow-based approaches. TRAC -Trends in Analytical Chemistry, 27(9), 749-761. DOI: 10.1016749-761. DOI: 10. /j.trac.2008 TrAC MS:08-00052-REVISED Abstract: Solid-phase extraction (SPE) has been consolidated as the most versatile sample processing method for removal of interfering species and/or analyte enrichment. Although significant advances have been conducted over the past two decades for automation of the entire analytical protocol involving SPE via flow injection approaches, on-line SPE assays performed in a permanent mode lack sufficient reliability as a consequence of the progressive tighter packing of the bead reactor, contamination of the solid surfaces and potential leakage of functional moieties. This article overviews the current state-of-the-art of an appealing tool for overcoming the above shortcomings, the so-called bead injection (BI) analysis, based on automated renewal of the sorbent material per assay exploiting the various generations of flow injection analysis. It addresses novel instrumental developments for implementation of BI and a number of alternatives for on-line chemical derivatization reactions and pinpoints the most common instrumental detection techniques utilised. Relevant environmental and bioanalytical applications reported within the past few years are presented and discussed in detail.

show abstract

Section: Fi-bi With Home Made and Commercial Flow Cellsmentioning

confidence: 99%

Section: Fi-bi With Home Made and Commercial Flow Cellsmentioning

confidence: 99%

Section: Analytical Procedures For Bead Injection 51 Bead Modificationmentioning

confidence: 99%

Section: Analyte Uptakementioning

confidence: 99%

Section: Detection Techniquesmentioning

confidence: 99%

See 3 more Smart Citations

Recent developments in automatic solid-phase extraction with renewable surfaces exploiting flow-based approaches

Miró

Hartwell

Jakmunee

et al. 2008

TrAC Trends in Analytical Chemistry

View full text Add to dashboard Cite

show abstract

A spectrophotometric method for the determination of zinc, copper, and cobalt ions in metalloproteins using Zincon

Säbel¹,

Neureuther²,

Siemann³

2010

Analytical Biochemistry

172

123

View full text Add to dashboard Cite

Recent trends in solid phase spectrometry: 2003–2009. A Review

Matsuoka

Yoshimura

2010

Analytica Chimica Acta

View full text Add to dashboard Cite

Around 100 papers published from 2003 to the present are reviewed concerning analytical methods for the direct light measurement of a solid phase in which a target colored or fluorescent analyte is concentrated. Recent attention has been paid to the development of flow injection-solid phase spectrometry as a simple and inexpensive tool for routine analysis of organic compounds or pharmaceuticals. Due to some improvements in flow injection analysis, such as sequential injection and lab-on-a-valve, it is possible not only to reduce the reagent consumption but also to devise fully automatic and miniaturized systems with minimal maintenance needs. This may have the potential of becoming one of the green analytical methods. Flow injection-solid phase spectrometry is expected to be applied to the speciation of trace chemical components (e.g., specific determination of trace metal ions in different existent oxidation states) in real samples in the environment.

show abstract

Resolution of Biparametric Mixtures Using Bead Injection Spectroscopic Flow-through Renewable Surface Sensors

Cited by 17 publications

References 28 publications

Recent developments in automatic solid-phase extraction with renewable surfaces exploiting flow-based approaches

Recent developments in automatic solid-phase extraction with renewable surfaces exploiting flow-based approaches

A spectrophotometric method for the determination of zinc, copper, and cobalt ions in metalloproteins using Zincon

Recent trends in solid phase spectrometry: 2003–2009. A Review

Contact Info

Product

Resources

About