2004
DOI: 10.1002/lt.20282
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Resolution of alcoholic neuropathy following liver transplantation

Abstract: Between 10 and 20% of adult liver transplants are performed for end-stage alcoholic liver disease. Severe extrahepatic end-organ damage from alcoholism (cardiomyopathy, pancreatitis, central nervous system injury, and neuropathy) is widely regarded as an absolute contraindication to liver transplantation, despite a lack of data on the effect of transplantation on these complications. We describe such a patient who presented with decompensated alcoholic liver disease and moderately severe peripheral neuropathy.… Show more

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Cited by 16 publications
(4 citation statements)
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“…Because alcohol-induced toxic neuropathy is relatively common in patients with alcoholic cirrhosis, 14,15 we speculated that these patients may demonstrate a higher incidence of postoperative neuropraxia. However, this was not the case, and indeed neuropraxia was not associated with any specific etiology for liver disease.…”
Section: Discussionmentioning
confidence: 99%
“…Because alcohol-induced toxic neuropathy is relatively common in patients with alcoholic cirrhosis, 14,15 we speculated that these patients may demonstrate a higher incidence of postoperative neuropraxia. However, this was not the case, and indeed neuropraxia was not associated with any specific etiology for liver disease.…”
Section: Discussionmentioning
confidence: 99%
“…Correction of metabolic disturbances and functioning allograft may result in an improvement of diabetic and alcoholic neuropathy in pancreas and liver allograft recipients [84,85]. Worsening of weakness and diabetic neuropathy after kidney and pancreas transplantation in some patients has been attributed to superimposed myopathy (probably critical illness myopathy) [86].…”
Section: Neuromuscular Complicationsmentioning
confidence: 99%
“…Recovery may require many months, and can be almost complete, but liver transplantation may be required in decompensated alcoholic cirrhosis, since the aforementioned remedies alone are insufficient [17].…”
Section: Clinical Featuresmentioning
confidence: 99%