Resolution improvement in microscopic imaging through turbid media based on differential polarization gating

Schilders, S. P.; Gan, Xiaosong; Gu, Miṅ

doi:10.1364/ao.37.004300

Cited by 29 publications

(17 citation statements)

References 11 publications

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“…In many experiments, detection of the polarization difference is employed (see, e.g., [13][14][15][16]19,[21][22][23][24][25]). This method is based on subtracting of the intensity of the cross-polarized component from the intensity of radiation with the initial polarization.…”

Section: Time-resolved Polarization Imagingmentioning

confidence: 99%

“…In the polarization-difference techniques (see, e.g., [13][14][15][16]19,[23][24][25]) the 'imagebearing' component of light is extracted by subtracting the detected cross-polarized signal from the co-polarized one. As diffusive photons with completely randomized polarization make the same contribution to both polarized components of scattered radiation, subtraction of cross-polarized component from the co-polarized one filters out the diffusive photons from the ballistic and snake photons.…”

Section: Introductionmentioning

confidence: 99%

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Transillumination of highly scattering media by polarized light

Gorodnichev

Ivliev

Kuzovlev

et al. 2013

Light Scattering Reviews 8

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Section: Time-resolved Polarization Imagingmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Transillumination of highly scattering media by polarized light

Gorodnichev

Ivliev

Kuzovlev

et al. 2013

Light Scattering Reviews 8

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“…Using Monte Carlo simulation of polarized light transport and by carrying out experimental studies on scattering samples prepared using monodisperse spherical scatterers, they investigated the possibility of utilizing degree of polarization to discriminate against multiply scattered light. Motivated by the encouraging results of this pioneering study, several theoretical [11][12][13][14][15]35,36] and experimental investigations [18][19][20][21][22]47,48] have been carried out to develop optimal polarization scheme for imaging through tissue. We shall summarize these with representative results.…”

Section: Depolarization Of Light In Turbid Medium and The Efficiency mentioning

confidence: 99%

Turbid medium polarimetry in biomedical imaging and diagnosis

Ghosh

Banerjee

Soni

2011

Eur. Phys. J. Appl. Phys.

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Abstract. Studies on polarization properties of scattered light from a random medium like biological tissue have received considerable attention because polarization can be used as an effective tool to discriminate against multiply scattered light (acting as a gating mechanism) and thus can facilitate high resolution imaging through tissue. Further, the polarization properties of scattered light from tissue contain wealth of morphological and functional information of potential biomedical importance. However, in a complex random medium like tissue, numerous complexities due to multiple scattering and simultaneous occurrences of many scattering and polarization events present formidable challenges both in terms of accurate measurements and in terms of analysis of the tissue polarimetry signal. Several studies have therefore been conducted in the recent past to develop appropriate measurement procedures, suitable light propagation models and polarimetry signal analysis methods to overcome these difficulties. In this review, we focus on some of the recent key developments in this area. Specifically, we describe variety of theoretical and experimental tools, illustrated with selected results, aimed at evaluating the prospect of turbid medium polarimetry for both biomedical imaging and diagnosis.

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“…Various investigators have suggested that the degree of polarization can be used as a discrimination criterion by which to extract weakly scattered from the multiply scattered light [1][2][3] and improve the image quality [4,5]. This method is based on the depolarization effect in random scattering of tissues.…”

Section: Introductionmentioning

confidence: 99%

<title>Polarization-based microscopy using a fiber optic spectral polarimeter</title>

2002

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ABSTRCTWe present a fiber optic spectral polarimeter, an instrument that allows measurement of the spectrally resolved Stokes parameters. The instrument consists of a pair of polarization maintaining (PM) fibers spliced at 45° with respect to each other in line with a polarizer module whose transmission axis is aligned to the fast axis of the first PM fiber. The generated spectrum is composed of three quasi-cosinusoidal components, which carry information required to reconstruct the spectrally resolved Stokes parameters of incident light. Fourier transform of the measured spectrum provides the significant parameters for determination of the spectrally resolved Stokes parameters of light. The performance of the fiber optic spectral polarimeter is demonstrated by the computer simulation and experiments with input light of known polarization states. A unique characteristic of this instrument is that the spectrally resolved polarization state of incident light can be determined from one spectral measurent without any mechanical movement. Moreover, the instrument can be incorporated into a tomographic imaging system such as a conventional microscopy system. Polarization based microscopy combined with a fiber optic spectral polarimeter will provide measurements that allow better understanding of depolarization process of light passing through biological materials for diagnostic imaging.

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Resolution improvement in microscopic imaging through turbid media based on differential polarization gating

Cited by 29 publications

References 11 publications

Transillumination of highly scattering media by polarized light

Transillumination of highly scattering media by polarized light

Turbid medium polarimetry in biomedical imaging and diagnosis

<title>Polarization-based microscopy using a fiber optic spectral polarimeter</title>

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